Evidence map›Paper›PMID 33919382›Full record

ArticleInternational journal of molecular sciences2021

Estrogen-Related Receptor Influences the Hemolymph Glucose Content by Regulating Midgut Trehalase Gene Expression in the Last Instar Larvae of

Guanwang Shen, Jinxin Wu, Ying Lin, Xiaoting Hua, Qingyou Xia, Ping Zhao

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Guanwang ShenBiological Science Research Center, Southwest University, Chongqing 400716, China.
Jinxin WuBiological Science Research Center, Southwest University, Chongqing 400716, China.
Ying LinBiological Science Research Center, Southwest University, Chongqing 400716, China.
Xiaoting HuaBiological Science Research Center, Southwest University, Chongqing 400716, China.
Qingyou XiaBiological Science Research Center, Southwest University, Chongqing 400716, China.ORCID 0000-0002-9263-2886
Ping ZhaoBiological Science Research Center, Southwest University, Chongqing 400716, China.
Southwest University · CN

Funding

Doctoral Fund Project of Southwest University 7110300034the National Natural Science Foundation of China 31530071the National Natural Science Foundation of China 31772532the National Natural Science Foundation of China 32030103
6 · The paper itself

Abstract

The expression of trehalase in the midgut of insects plays an important role in glucose supply to the hemolymph. Energy metabolism is usually regulated by the estrogen-related receptor (ERR). A decrease in ATP levels is caused by the ERR hindering glycolysis. However, the relationship between trehalose accumulation and ERR expression is still unclear. Here, we found that silkworm ERR (BmERR) is concentrated and BmERR expression is strongly correlated with trehalase in the midgut during the last instar silkworm larval stage. We cloned the promoter of the trehalase from

Indexed as

Gene Expression Regulation, EnzymologicAnimalsBombyxDigestive SystemERRalpha Estrogen-Related ReceptorGlucoseHemolymphInsect ProteinsLarvaReceptors, EstrogenTrehalaseTrehaloseERRalpha Estrogen-Related ReceptorGlucoseInsect ProteinsReceptors, EstrogenTrehalaseTrehaloseestrogen-related receptorhemolymph glucosesilkwormtranscriptional regulationtrehalase

Identifiers

PMID33919382
PMCPMC8122577
OpenAlexW3153101969

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.