ArticleViruses2021
SARS-CoV-2 and Placenta: New Insights and Perspectives.
Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Meta-analysis on COVID-19-pregnancy-related placental pathologies shows no specific pattern.Placenta · 2022Pooled it
- Placental histopathology after SARS-CoV-2 infection in pregnancy: a systematic review and meta-analysis.American journal of obstetrics & gynecology MFM · 2021Pooled it
- RT-qPCR detection of SARS-CoV-2 RNA in placentas of women with spontaneous abortion: a retrospective pilot study.BMC pregnancy and childbirth · 2026Article
- The placental battlefield: viral strategies and immune countermeasures.Frontiers in immunology · 2025Review
- Placental ACE2 Expression: A Possible Pathogenetic Mechanism for Infantile Hemangiomas.Dermatopathology (Basel, Switzerland) · 2024Article
- Impact of COVID-19 disease on placental histopathology. PLAXAVID study.Histology and histopathology · 2024Observational
- Article
- Impact of COVID-19 on Fetal Outcomes in Pregnant Women: A Systematic Review and Meta-Analysis.Journal of personalized medicine · 2023Review
- Use of Sotrovimab in a cohort of pregnant women with a high risk of COVID 19 progression: a single-center experience.Pathogens and global health · 2023Article
- Article
- Antepartum SARS-CoV-2 infection and adverse birth outcomes in South African women.Journal of global health · 2022Article
- Article
- COVID-19 in Pregnant Women, Maternal-Fetal Involvement, and Vertical Mother-to-Child Transmission: A Systematic Review.Biomedicines · 2022Review
- A Review of the Prevalence of Thromboembolic Complications among Pregnant Women Infected with COVID-19.Journal of clinical medicine · 2022Review
- Article
- Cardiovascular Factors Associated with COVID-19 from an International Registry of Primarily Japanese Patients.Diagnostics (Basel, Switzerland) · 2022Article
- SARS-CoV-2 and Skin: New Insights and Perspectives.Biomolecules · 2022Review
- SARS-CoV-2 Infection in Pregnancy: Placental Histomorphological Patterns, Disease Severity and Perinatal Outcomes.International journal of environmental research and public health · 2022Article
- Gestational SARS-CoV-2 infection is associated with placental expression of immune and trophoblast genes.Placenta · 2022Article
- RNA Viruses, Pregnancy and Vaccination: Emerging Lessons from COVID-19 and Ebola Virus Disease.Pathogens (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study of SARS-CoV-2 positive pregnant women is of some importance for gynecologists, obstetricians, neonatologists and women themselves. In recent months, new works have tried to clarify what happens at the fetal-placental level in women positive for the virus, and different pathogenesis mechanisms have been proposed. Here, we present the results of a large series of placentas of Coronavirus disease (COVID) positive women, in a reference center for COVID-positive pregnancies, on which we conducted histological, immunohistochemical and electron microscopy investigations. A case-control study was conducted in order to highlight any histopathological alterations attributable to SARS-CoV-2. The prevalence of maternal vascular malperfusion was not significantly different between cases and controls (54.3% vs. 43.7%
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.