ArticleNanomaterials (Basel, Switzerland)2021
Characteristics of P-Type and N-Type Photoelectrochemical Biosensors: A Case Study for Esophageal Cancer Detection.
Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Investigation of 2H/1T/1T' phase MoSDiscover nano · 2025Article
- Applications and development trend of biosensors in the detection and diagnosis of gastrointestinal tumors.Biomedical engineering online · 2025Review
- Lung cancer cells detection by a photoelectrochemical MoSBiomedical optics express · 2024Article
- Advancement in Biosensor Technologies of 2D MaterialIntegrated with Cellulose-Physical Properties.Micromachines · 2023Review
- Systematic meta-analysis of computer-aided detection to detect early esophageal cancer using hyperspectral imaging.Biomedical optics express · 2023Article
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Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
Abstract
P-type and N-type photoelectrochemical (PEC) biosensors were established in the laboratory to discuss the correlation between characteristic substances and photoactive material properties through the photogenerated charge carrier transport mechanism. Four types of human esophageal cancer cells (ECCs) were analyzed without requiring additional bias voltage. Photoelectrical characteristics were examined by scanning electron microscopy (SEM), X-ray diffraction (XRD), UV-vis reflectance spectroscopy, and photocurrent response analyses. Results showed that smaller photocurrent was measured in cases with advanced cancer stages. Glutathione (L-glutathione reduced, GSH) and Glutathione disulfide (GSSG) in cancer cells carry out redox reactions during carrier separation, which changes the photocurrent. The sensor can identify ECC stages with a certain level of photoelectrochemical response. The detection error can be optimized by adjusting the number of cells, and the detection time of about 5 min allowed repeated measurement.
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