Evidence map›Paper›PMID 33919096›Full record

ReviewCancers2021

Carbon Dots as Promising Tools for Cancer Diagnosis and Therapy.

Giuseppe Nocito, Giovanna Calabrese, Stefano Forte, Salvatore Petralia, Caterina Puglisi, Michela Campolo, Emanuela Esposito, Sabrina Conoci

Abstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
  2. Review
  3. Review of Antimicrobial Properties of Carbon Nanomaterials.International journal of molecular sciences · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Synthesis of High Fluorescent Carbon Dots by Laser Ablation of Bay Leaves in Biocompatible Solutions.Luminescence : the journal of biological and chemical luminescence · 2025
    Article
  10. Potential of Carbon Nanodots (CNDs) in Cancer Treatment.Nanomaterials (Basel, Switzerland) · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giuseppe NocitoDepartment of Chemistry, Biology, Pharmacy and Environmental Science, University of Messina, 98122 Messina, Italy.ORCID 0000-0002-1659-4697
Giovanna CalabreseDepartment of Chemistry, Biology, Pharmacy and Environmental Science, University of Messina, 98122 Messina, Italy.ORCID 0000-0003-1937-5403
Stefano ForteIOM Ricerca, Viagrande, 95029 Catania, Italy.ORCID 0000-0001-5746-7451
Salvatore PetraliaDepartment of Drug Science and Health, University of Catania, 95125 Catania, Italy.
Caterina PuglisiIOM Ricerca, Viagrande, 95029 Catania, Italy.ORCID 0000-0003-1991-0082
Michela CampoloDepartment of Chemistry, Biology, Pharmacy and Environmental Science, University of Messina, 98122 Messina, Italy.
Emanuela EspositoDepartment of Chemistry, Biology, Pharmacy and Environmental Science, University of Messina, 98122 Messina, Italy.ORCID 0000-0002-2663-6387
Sabrina ConociDepartment of Chemistry, Biology, Pharmacy and Environmental Science, University of Messina, 98122 Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon Dots (CDs) are the latest members of carbon-based nanomaterials, which since their discovery have attracted notable attention due to their chemical and mechanical properties, brilliant fluorescence, high photostability, and good biocompatibility. Together with the ease and affordable preparation costs, these intrinsic features make CDs the most promising nanomaterials for multiple applications in the biological field, such as bioimaging, biotherapy, and gene/drug delivery. This review will illustrate the most recent applications of CDs in the biomedical field, focusing on their biocompatibility, fluorescence, low cytotoxicity, cellular uptake, and theranostic properties to highlight above all their usefulness as a promising tool for cancer diagnosis and therapy.

Indexed as

bioimagingcancer diagnosis cancer therapycarbon dotsdrug deliveryphotodynamic therapyphotothermal therapy

Identifiers

PMID33919096
PMCPMC8122497

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.