Evidence map›Paper›PMID 33919094›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Automated CT Lung Density Analysis of Viral Pneumonia and Healthy Lungs Using Deep Learning-Based Segmentation, Histograms and HU Thresholds.

Andrej Romanov, Michael Bach, Shan Yang, Fabian C Franzeck, Gregor Sommer, Constantin Anastasopoulos, Jens Bremerich, Bram Stieltjes, Thomas Weikert, Alexander Walter Sauter

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Andrej RomanovDepartment of Radiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0003-1404-6950
Michael BachDepartment of Research & Analytic Services, University Hospital Basel, University of Basel, Spitalstrasse 8, 4031 Basel, Switzerland.
Shan YangDepartment of Research & Analytic Services, University Hospital Basel, University of Basel, Spitalstrasse 8, 4031 Basel, Switzerland.
Fabian C FranzeckDepartment of Research & Analytic Services, University Hospital Basel, University of Basel, Spitalstrasse 8, 4031 Basel, Switzerland.
Gregor SommerDepartment of Radiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0002-8952-0808
Constantin AnastasopoulosDepartment of Radiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0001-9818-2460
Jens BremerichDepartment of Radiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.
Bram StieltjesDepartment of Research & Analytic Services, University Hospital Basel, University of Basel, Spitalstrasse 8, 4031 Basel, Switzerland.ORCID 0000-0002-5961-802X
Thomas WeikertDepartment of Radiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0001-9274-053X
Alexander Walter SauterDepartment of Radiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0002-6707-2258
University of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CT patterns of viral pneumonia are usually only qualitatively described in radiology reports. Artificial intelligence enables automated and reliable segmentation of lungs with chest CT. Based on this, the purpose of this study was to derive meaningful imaging biomarkers reflecting CT patterns of viral pneumonia and assess their potential to discriminate between healthy lungs and lungs with viral pneumonia. This study used non-enhanced and CT pulmonary angiograms (CTPAs) of healthy lungs and viral pneumonia (SARS-CoV-2, influenza A/B) identified by radiology reports and RT-PCR results. After deep learning segmentation of the lungs, histogram-based and threshold-based analyses of lung attenuation were performed and compared. The derived imaging biomarkers were correlated with parameters of clinical and biochemical severity (modified WHO severity scale; c-reactive protein). For non-enhanced CTs (

Indexed as

artificial intelligencecomputed tomographyhistogram analysisimaging biomarkerviral pneumonia

Identifiers

PMID33919094
PMCPMC8143124
OpenAlexW3152958266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.