ReviewNutrients2021
Effects of Oro-Sensory Exposure on Satiation and Underlying Neurophysiological Mechanisms-What Do We Know So Far?
Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Chewing Gum on Satiety, Appetite Regulation, Energy Intake, and Weight Loss: A Systematic Review.Nutrients · 2025Pooled it
- Eating rate has sustained effects on energy intake from ultraprocessed diets: a 2-week ad libitum dietary randomized controlled crossover trial.The American journal of clinical nutrition · 2026Trial
- Trial
- Metabolic Effects and Safety Aspects of Acute D-allulose and Erythritol Administration in Healthy Subjects.Nutrients · 2023Trial
- Characterization and Comparison of Dietary Taste Patterns in Five Countries With Differing Obesity Prevalence.Food science & nutrition · 2026Article
- Development and Validation of the Food Consumption Rate Questionnaire (FCRQ): A Behaviorally Informed Measure of Eating-Rate Regulation.Nutrients · 2026Article
- Effect of theFoods (Basel, Switzerland) · 2026Article
- Altered eating experience during GLP-1 receptor agonist therapy: a sensory-liking-wanting framework for food preference and nutritional behaviour.Frontiers in nutrition · 2026Review
- Effects of Interoceptive and Exteroceptive Attention Training on Desire-Driven Eating in Healthy Adults: A Quasi-Experimental Early-Stage Feasibility Study.Foods (Basel, Switzerland) · 2025Article
- The role of ultra-processed food in obesity.Nature reviews. Endocrinology · 2025Review
- Savoring Satiety: An Exploratory Analysis of the Neural Correlates of Sensory-Specific Satiety.Nutrients · 2025Article
- Glucagon-Like Peptide-1 and Hypothalamic Regulation of Satiation: Cognitive and Neural Insights from Human and Animal Studies.Diabetes & metabolism journal · 2025Review
- Hallmarks of Appetite: A Comprehensive Review of Hunger, Appetite, Satiation, and Satiety.Current obesity reports · 2025Review
- PACE: a Novel Eating Behavior Phenotype to Assess Risk for Obesity in Middle Childhood.The Journal of nutrition · 2024Article
- Child eating behaviors are consistently linked to intake across meals that vary in portion size.Appetite · 2024Article
- Satiating Capacity of Plant-Based Meat in Realistic Meal Contexts at Home.Foods (Basel, Switzerland) · 2023Article
- Speed limits: the effects of industrial food processing and food texture on daily energy intake and eating behaviour in healthy adults.European journal of nutrition · 2023Article
- Dissecting ultra-processed foods and drinks: Do they have a potential to impact the brain?Reviews in endocrine & metabolic disorders · 2022Review
- Appetite and Satiety Control-Contribution of Gut Mechanisms.Nutrients · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The mouth is the first part of the gastrointestinal tract. During mastication sensory signals from the mouth, so-called oro-sensory exposure, elicit physiological signals that affect satiation and food intake. It has been established that a longer duration of oro-sensory exposure leads to earlier satiation. In addition, foods with more intense sweet or salty taste induce earlier satiation compared to foods that are equally palatable, but with lower taste intensity. Oro-sensory exposure to food affects satiation by direct signaling via the brainstem to higher cortical regions involved in taste and reward, including the nucleus accumbens and the insula. There is little evidence that oro-sensory exposure affects satiation indirectly through either hormone responses or gastric signals. Critical brain areas for satiation, such as the brainstem, should be studied more intensively to better understand the neurophysiological mechanisms underlying the process of satiation. Furthermore, it is essential to increase the understanding of how of highly automated eating behaviors, such as oral processing and eating rate, are formed during early childhood. A better understanding of the aforementioned mechanisms provides fundamental insight in relation to strategies to prevent overconsumption and the development of obesity in future generations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.