Evidence map›Paper›PMID 33918998›Full record

ArticleJournal of personalized medicine2021

Development of a Fundus Image-Based Deep Learning Diagnostic Tool for Various Retinal Diseases.

Kyoung Min Kim, Tae-Young Heo, Aesul Kim, Joohee Kim, Kyu Jin Han, Jaesuk Yun, Jung Kee Min

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kyoung Min KimData Scientist Team, BEGAS Inc., Sejong-daero 39, Jung-gu, Seoul 04513, Korea.
Tae-Young HeoDepartment of Information and Statistics, Chungbuk National University, Chungdae-ro 1, Seowon-gu, Cheongju-si, Chungbuk 28644, Korea.ORCID 0000-0002-0505-5559
Aesul KimLaboratory of Pharmacology, College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungbuk 28160, Korea.
Joohee KimLaboratory of Pharmacology, College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungbuk 28160, Korea.
Kyu Jin HanDepartment of Ophthalmology, Ulsan University Hospital, College of Medicine, University of Ulsan, 877, Bangeojinsunhwando-ro, Dong-gu, Ulsan 44033, Korea.
Jaesuk YunLaboratory of Pharmacology, College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungbuk 28160, Korea.
Jung Kee MinDepartment of Ophthalmology, Ulsan University Hospital, College of Medicine, University of Ulsan, 877, Bangeojinsunhwando-ro, Dong-gu, Ulsan 44033, Korea.ORCID 0000-0002-8006-8560

Funding

National Research Foundation of Korea 2017R1C1B5017929
6 · The paper itself

Abstract

Artificial intelligence (AI)-based diagnostic tools have been accepted in ophthalmology. The use of retinal images, such as fundus photographs, is a promising approach for the development of AI-based diagnostic platforms. Retinal pathologies usually occur in a broad spectrum of eye diseases, including neovascular or dry age-related macular degeneration, epiretinal membrane, rhegmatogenous retinal detachment, retinitis pigmentosa, macular hole, retinal vein occlusions, and diabetic retinopathy. Here, we report a fundus image-based AI model for differential diagnosis of retinal diseases. We classified retinal images with three convolutional neural network models: ResNet50, VGG19, and Inception v3. Furthermore, the performance of several dense (fully connected) layers was compared. The prediction accuracy for diagnosis of nine classes of eight retinal diseases and normal control was 87.42% in the ResNet50 model, which added a dense layer with 128 nodes. Furthermore, our AI tool augments ophthalmologist's performance in the diagnosis of retinal disease. These results suggested that the fundus image-based AI tool is applicable for the medical diagnosis process of retinal diseases.

Indexed as

artificial intelligenceclass activation mapconvolutional neural networkfundus photographretinal diseases

Identifiers

PMID33918998
PMCPMC8142986

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.