Evidence map›Paper›PMID 33918949›Full record

ArticleJournal of clinical medicine2021

Calcium Channel Blockers Are Associated with Nocturia in Men Aged 40 Years or Older.

Satoshi Washino, Yusuke Ugata, Kimitoshi Saito, Tomoaki Miyagawa

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Nocturia and sleep blood pressure - A key link in a vicious cycle?Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  3. Insights into the associative role of hypertension and angiotensin II receptor in lower urinary tract dysfunction.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Satoshi WashinoDepartment of Urology, Jichi Medical University Saitama Medical Center, Saitama 330-8503, Japan.ORCID 0000-0001-9464-6424
Yusuke UgataDepartment of Cardiology, Jichi Medical University Saitama Medical Center, Saitama 330-8503, Japan.
Kimitoshi SaitoDepartment of Urology, Jichi Medical University Saitama Medical Center, Saitama 330-8503, Japan.
Tomoaki MiyagawaDepartment of Urology, Jichi Medical University Saitama Medical Center, Saitama 330-8503, Japan.
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe associations of nocturia with hypertension and anti-hypertensive agents (AHTs) remain to be validated.

methodsThis cross-sectional study examined whether blood pressure and/or frequently used classes of AHTs had consistent associations with nocturia.

methodsA total of 418 male patients aged ≥ 40 years were retrospectively assessed in terms of the International Prostate Symptom Score (IPSS), prescription medications, and blood pressure. Nocturia was evaluated using item 7 of the IPSS, and two or more episodes of nocturia per night was considered to indicate clinically important nocturia.

resultsPatients taking calcium channel blockers (CCBs), but not other AHTs, experienced more episodes of nocturia than patients not taking AHTs (1.77 ± 1.07, 1.90 ± 1.19, and 1.48 ± 0.98 in CCBs alone, CCBs + other AHTs, and other AHTs alone, vs. 1.35 ± 1.08 in not taking AHTs;

conclusionCCB was associated with nocturia, while AHTs other than CCBs and elevated blood pressure were not.

Indexed as

anti-hypertensive agentsblood pressurecalcium channel blockerhypertensionnocturia

Identifiers

PMID33918949
PMCPMC8070101
OpenAlexW3156514701

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.