Evidence map›Paper›PMID 33918895›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Sub-Inhibitory Concentrations of Ciprofloxacin Alone and Combinations with Plant-Derived Compounds against

Didem Kart, Tuba Reçber, Emirhan Nemutlu, Meral Sagiroglu

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Metabolomic Insights of Biosurfactant Activity fromInternational journal of molecular sciences · 2023
    Article
  14. Gentamicin Augments the Quorum Quenching Potential of CinnamaldehydeFrontiers in cellular and infection microbiology · 2022
    Article
  15. Frontiers in cellular and infection microbiology · 2022
    Review
  16. Frontiers in pharmacology · 2022
    Article
  17. Article
  18. Frontiers in endocrinology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Didem KartDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Hacettepe University, Ankara 06100, Turkey.ORCID 0000-0001-7119-5763
Tuba ReçberDepartment of Analytical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara 06100, Turkey.
Emirhan NemutluDepartment of Analytical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara 06100, Turkey.
Meral SagirogluDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Hacettepe University, Ankara 06100, Turkey.
Hacettepe University · TR

Funding

Türkiye Bilimsel ve Teknolojik Araştirma Kurumu 115S550
6 · The paper itself

Abstract

introductionAlternative anti-biofilm agents are needed to combat MATERIALS AND

methodsThe anti-biofilm effects of 10 plant-derived compounds on

resultsThe combinations of ciprofloxacin with curcumin, baicalein, esculetin, and cinnamaldehyde showed more reduced MBICs than ciprofloxacin alone. The quorum sensing genes were downregulated in the presence of curcumin and cinnamaldehyde, while upregulated in the presence of baicalein and esculin hydrate rather than for ciprofloxacin alone. The combinations exhibited different killing effects on

conclusionsThe use of curcumin, baicalein, esculetin, and cinnamaldehyde with ciprofloxacin will help fight against

Indexed as

biofilmMBICmetabolomicP. aeruginosaplant-derived compounds

Identifiers

PMID33918895
PMCPMC8070142
OpenAlexW3156596315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.