Evidence map›Paper›PMID 33918842›Full record

ArticleDentistry journal2021

Efficacy of EDTA and HEDP Chelators in the Removal of Mature Biofilm of

Alejandro Álvarez-Sagües, Nerea Herce, Ulises Amador, Francisco Llinares-Pinel, Estanislao Nistal-Villan, Jesús Presa, Laura Álvarez, Magdalena Azabal

Open access · goldAbstract read
In one paragraph

Article in Dentistry journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Alejandro Álvarez-SagüesDentistry Department, Faculty of Medicine, San Pablo CEU University, 28668 Madrid, Spain.
Nerea HerceDentistry Department, Faculty of Medicine, San Pablo CEU University, 28668 Madrid, Spain.
Ulises AmadorDepartamento de Química y Bioquímica, Facultad de Farmacia, Universidad San Pablo-CEU, Urbanización Montepríncipe, Boadilla del Monte, 28668 Madrid, Spain.ORCID 0000-0002-4412-2419
Francisco Llinares-PinelMicrobiology Section, Departamento CC, Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad CEU San Pablo, Boadilla del Monte, 28668 Madrid, Spain.
Estanislao Nistal-VillanMicrobiology Section, Departamento CC, Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad CEU San Pablo, Boadilla del Monte, 28668 Madrid, Spain.ORCID 0000-0003-2458-8833
Jesús PresaIndependent Researcher, 28668 Madrid, Spain.ORCID 0000-0002-6511-7811
Laura ÁlvarezDentistry Department, Faculty of Medicine, San Pablo CEU University, 28668 Madrid, Spain.
Magdalena AzabalDentistry Department, Faculty of Medicine, San Pablo CEU University, 28668 Madrid, Spain.ORCID 0000-0002-1494-821X
Universidad San Pablo CEU · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBiofilm removal from the root canal during endodontic treatment is necessary to prevent further complications. Irrigation is essential to success. Several irrigants have been proposed without a proper comparison. The aim of the study is to compare the antibacterial capacity of different activated irrigants using passive ultrasonic activation (PUI) or XP-Endo finisher (XPF).

methodsA total of 100 instrumented teeth were incubated in an Eppendorf tube containing 0.5 McFarland of

resultsAs compared to the untreated control group, the irrigators included in the study had a significant effect in bacteria reduction. The obtained results show HEDP to be the most effective irrigant, since no bacteria were recovered after treatment of this group, followed by EDTA mixed with NaOCl and, finally, the EDTA-irrigated group.

conclusionsHEDP is the best irrigating agent in combination with XPF or PUI file activation to eliminate bacteria in our experimental model.

Indexed as

EDTAEndo-XP finisher (XPF)Enterococcus faecalisethydronic acid (HEDP)passive ultrasonic activation (PUI)

Identifiers

PMID33918842
PMCPMC8068811
OpenAlexW3155788607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.