Evidence map›Paper›PMID 33918816›Full record

ArticleGenes2021

Neuropilin-2 and Its Transcript Variants Correlate with Clinical Outcome in Bladder Cancer.

Sarah Förster, Maryam Givehchi, Katja Nitschke, Thomas Mayr, Kerstin Kilian, Samikshan Dutta, Kaustubh Datta, Philipp Nuhn, Zoran Popovic, Michael H Muders and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Role ofFrontiers in genetics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Sarah FörsterRudolf Becker Laboratory for Prostate Cancer Research, Institute of Pathology, University of Bonn Medical Center, 53127 Bonn, Germany.
Maryam GivehchiDepartment of Urology and Urosurgery, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Katja NitschkeDepartment of Urology and Urosurgery, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Thomas MayrRudolf Becker Laboratory for Prostate Cancer Research, Institute of Pathology, University of Bonn Medical Center, 53127 Bonn, Germany.
Kerstin KilianDepartment of Urology and Urosurgery, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Samikshan DuttaDepartment of Biochemistry, University of Nebraska Medical Center, Omaha, NE 68198-5870, USA.
Kaustubh DattaDepartment of Biochemistry, University of Nebraska Medical Center, Omaha, NE 68198-5870, USA.
Philipp NuhnDepartment of Urology and Urosurgery, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Zoran PopovicInstitute of Pathology, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Michael H MudersRudolf Becker Laboratory for Prostate Cancer Research, Institute of Pathology, University of Bonn Medical Center, 53127 Bonn, Germany.
Philipp ErbenDepartment of Urology and Urosurgery, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.ORCID 0000-0002-8279-7636
Heidelberg University · DEUniversity of Bonn · DEUniversity of Nebraska Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urothelial bladder cancer ranks among the 10 most frequently diagnosed cancers worldwide. In our previous study, the transmembrane protein neuropilin-2 (NRP2) emerged as a predictive marker in patients with bladder cancer. NRP2 consists of several splice variants; the most abundant of these, NRP2a and NRP2b, are reported to have different biological functions in lung cancer progression. For other cancer types, there are no published data on the role of these transcript variants in cancer progression and the clinical outcome. Here, we correlate

Indexed as

Genetic VariationAgedAged, 80 and overBiomarkers, TumorFemaleFollow-Up StudiesGene Expression Regulation, NeoplasticHumansMaleMiddle AgedNeuropilin-2PrognosisProtein IsoformsRetrospective StudiesSurvival RateUrinary Bladder NeoplasmsBiomarkers, TumorNeuropilin-2neuropilin-2, humanProtein Isoformsbladder cancermuscle-invasive bladder cancer (MIBC)neuropilin-2 (NRP2)neuropilin-2 transcript variantsNRP2aplatelet-derived growth factor (PDGF)

Identifiers

PMID33918816
PMCPMC8070368
OpenAlexW3156144983

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.