Evidence map›Paper›PMID 33918796›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Antibiotic Use in Very Low Birth Weight Neonates After an Antimicrobial Stewardship Program.

Alberto Berardi, Isotta Zinani, Cecilia Rossi, Eugenio Spaggiari, Virginia D'Amico, Greta Toni, Luca Bedetti, Laura Lucaccioni, Lorenzo Iughetti, Licia Lugli

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. A systematic review of Perinatal Antibiotic Stewardship - where we are, where to go?Journal of perinatology : official journal of the California Perinatal Association · 2025
    Pooled it
  2. Article
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  4. Observational
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  11. Neonatal septic shock, a focus on first line interventions.Acta bio-medica : Atenei Parmensis · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alberto BerardiNeonatal Intensive Care Unit, University Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.ORCID 0000-0002-3534-7499
Isotta ZinaniPediatric Post-Graduate School, University Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.
Cecilia RossiNeonatal Intensive Care Unit, University Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.
Eugenio SpaggiariNeonatal Intensive Care Unit, University Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.
Virginia D'AmicoPediatric Post-Graduate School, University Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.
Greta ToniPediatric Post-Graduate School, University Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.
Luca BedettiNeonatal Intensive Care Unit, University Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.ORCID 0000-0003-1302-4944
Laura LucaccioniPediatric Department, University of Modena and Reggio Emilia, 41121 Modena, Italy.
Lorenzo IughettiPediatric Department, University of Modena and Reggio Emilia, 41121 Modena, Italy.ORCID 0000-0003-0370-7872
Licia LugliNeonatal Intensive Care Unit, University Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.
University of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is insufficient data regarding antimicrobial stewardship (AS) and outcomes of very low birth weight (VLBW) neonates after AS programs. This observational, retrospective study addressed AS and outcomes of VLBW neonates admitted to an Italian level-three center. Two periods were compared: (i) baseline, before AS (January 2011-December 2012) and (ii) intervention, after AS (January 2016-December 2017). Between these two periods, procedures were put in place to inform medical and nursing staff regarding AS. There were 111 and 119 VLBW neonates in the baseline (6744 live births) and in the intervention period (5902 live births), respectively. The number of infants exposed to antibiotics (70%) during the hospital stay did not change, but the total days of therapy (DOT, median 12 vs. 5) and DOT/1000 patient days (302 vs. 215) decreased in the intervention period (

Indexed as

antimicrobial stewardshipearly onset sepsislate onset sepsisnewbornvery low birth weight neonates

Identifiers

PMID33918796
PMCPMC8070476
OpenAlexW3156667707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.