Evidence map›Paper›PMID 33918756›Full record

ArticleJournal of cardiovascular development and disease2021

Persistent Ventricle Partitioning in the Adult Zebrafish Heart.

Catherine Pfefferli, Hannah R Moran, Anastasia Felker, Christian Mosimann, Anna Jaźwińska

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Getting to the Heart of Left-Right Asymmetry: Contributions from the Zebrafish Model.Journal of cardiovascular development and disease · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Catherine PfefferliDepartment of Biology, University of Fribourg, Chemin du Musée 10, 1700 Fribourg, Switzerland.
Hannah R MoranDepartment of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine and Children's Hospital Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0001-8056-5762
Anastasia FelkerDepartment of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine and Children's Hospital Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.
Christian MosimannDepartment of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine and Children's Hospital Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0002-0749-2576
Anna JaźwińskaDepartment of Biology, University of Fribourg, Chemin du Musée 10, 1700 Fribourg, Switzerland.ORCID 0000-0003-3881-9284
Children's Hospital Colorado · USUniversity of Fribourg · CH

Funding

Children's Hospital Colorado Foundation USANovartis Foundation for medical-biological research 18A032Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030_179213the Department of Pediatrics, University of Colorado School of Medicine Anschutz Medical Campus USA
6 · The paper itself

Abstract

The vertebrate heart integrates cells from the early-differentiating first heart field (FHF) and the later-differentiating second heart field (SHF), both emerging from the lateral plate mesoderm. In mammals, this process forms the basis for the development of the left and right ventricle chambers and subsequent chamber septation. The single ventricle-forming zebrafish heart also integrates FHF and SHF lineages during embryogenesis, yet the contributions of these two myocardial lineages to the adult zebrafish heart remain incompletely understood. Here, we characterize the myocardial labeling of FHF descendants in both the developing and adult zebrafish ventricle. Expanding previous findings, late gastrulation-stage labeling using

Indexed as

cardiac ventriclefirst heart fieldheart developmentlineage tracingzebrafish

Identifiers

PMID33918756
PMCPMC8070482
OpenAlexW3138235976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.