Evidence map›Paper›PMID 33918702›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Immune Response Visualized In Vivo by [18F]-FDG PET/CT after COVID-19 Vaccine.

Romain-David Seban, Laurence Champion, Nicolas Deleval, Capucine Richard, Claire Provost

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Prolonged generalized immune response onRadiology case reports · 2023
    Article
  3. [Diagnostics (Basel, Switzerland) · 2023
    Article
  4. Observational
  5. Absolute Lymphocyte Count After COVID-19 Vaccination Is Associated with Vaccine-Induced Hypermetabolic Lymph Nodes onJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Romain-David SebanDepartment of Nuclear Medicine and Endocrine Oncology, Institut Curie, 92210 Saint-Cloud, France.
Laurence ChampionDepartment of Nuclear Medicine and Endocrine Oncology, Institut Curie, 92210 Saint-Cloud, France.
Nicolas DelevalDepartment of Nuclear Medicine and Endocrine Oncology, Institut Curie, 92210 Saint-Cloud, France.
Capucine RichardDepartment of Nuclear Medicine and Endocrine Oncology, Institut Curie, 92210 Saint-Cloud, France.
Claire ProvostLaboratoire d'Imagerie Translationnelle en Oncologie, Inserm, Institut Curie, 91401 Orsay, France.ORCID 0000-0002-4390-4486
Inserm · FRInstitut Curie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide deployment of COVID-19 vaccines is in progress. Recent immune activation following vaccination can sometimes be seen in fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography ([18F]-FDG PET/CT). As previously evidenced, FDG-avid axillary lymph node(s) are common in patients receiving vaccines against SARS-CoV-2, influenza virus, or human papillomavirus, and reflect a regional immune response. In addition, these findings may also be accompanied by an increased spleen glucose metabolism after the COVID-19 vaccine, which captures a systemic immune response. Hence, we provide here a clinical example demonstrating that immune response could be associated with increased glucose metabolism in lymphoid organs such as lymph nodes and the spleen, which are critical modulators of T cell immunity. We believe that it is of paramount importance that nuclear physicians should be able to recognize clinical and imaging features of such immune responses upon vaccination for COVID-19 and beyond.

Indexed as

[18F]-FDG PET/CTCOVID-19 vaccineimmune responselymph nodesspleen

Identifiers

PMID33918702
PMCPMC8069156
OpenAlexW3153468128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.