ReviewNutrients2021
Metabolic Basis of Creatine in Health and Disease: A Bioinformatics-Assisted Review.
Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05697900 (Creatine Monohydrate Versus Creatine Hydrochloride on Strength and Body Composition in Elite Team-Sport Athletes), which is not on this map. Cited by 100 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Creatine Monohydrate Versus Creatine Hydrochloride on Strength and Body Composition in Elite Team-Sport Athletes: A Three-arm Placebo-controlled Randomized Clinical Trial
Who cites it
100 citing papers in PubMed, 4 syntheses or guidelines pooled it, 165 citations in OpenAlex.
- Does creatine affect lipid profile? a systematic review and meta-analysis of randomized placebo-controlled trials.Frontiers in nutrition · 2026Pooled it
- Creatine supplementation protocols with or without training interventions on body composition: a GRADE-assessed systematic review and dose-response meta-analysis.Journal of the International Society of Sports Nutrition · 2024Pooled it
- The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis.Frontiers in nutrition · 2024Pooled it
- Nutritional Strategies in the Rehabilitation of Musculoskeletal Injuries in Athletes: A Systematic Integrative Review.Nutrients · 2023Pooled it
- Effects of six weeks of guanidinoacetic acid supplementation with and without creatine monohydrate on cognitive function and markers of health in healthy adults.Journal of the International Society of Sports Nutrition · 2026Trial
- Effects of creatine supplementation with and without exercise and diet intervention on body composition, cognitive function, and markers of health in middle-aged and older adults.Journal of the International Society of Sports Nutrition · 2026Trial
- Single-Dose Creatine Reduces Sleep Deprivation-Induced Deterioration in Cognitive Performance.Nutrients · 2026Trial
- Trial
- Effects ofNutrients · 2025Trial
- Comparing effects of breathing exercises alone and combined with breathing-stretching exercises on respiratory indices, disease severity and exercise capacity in COPD.Scientific reports · 2025Trial
- Oral creatine in hemodialysis patients increases physical functional capacity and muscle mass, an open label study.PloS one · 2025Trial
- Effects of WatchingCardiovascular & hematological disorders drug targets · 2025Trial
- Multi-omics characterization of improved cognitive functions in Parkinson's disease patients after the combined metabolic activator treatment: a randomized, double-blinded, placebo-controlled phase II trial.Brain communications · 2025Trial
- A randomized open-labeled study to examine the effects of creatine monohydrate and combined training on jump and scoring performance in young basketball players.Journal of the International Society of Sports Nutrition · 2022Trial
- Trial
- Article
- Histology and matched multi-omics profiling resolve developmental transitions in Wugang Copper Goose leg muscle.Poultry science · 2026Article
- Article
- Quercetin Reduces Lipid Accumulation During Adipogenic Differentiation in Association with Stage-Dependent Mitochondrial-Redox and Metabolic Alterations Revealed by Time-ResolvedLife (Basel, Switzerland) · 2026Article
- Genome-wide association study of sarcopenia index reveals sex-stratified genetic architecture.Biology of sex differences · 2026Article
40 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Creatine (Cr) is a ubiquitous molecule that is synthesized mainly in the liver, kidneys, and pancreas. Most of the Cr pool is found in tissues with high-energy demands. Cr enters target cells through a specific symporter called Na
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.