Evidence map›Paper›PMID 33918523›Full record

ReviewPharmaceuticals (Basel, Switzerland)2021

Improving the Quality of Oocytes with the Help of Nucleolotransfer Therapy.

Michal Benc, Frantisek Strejcek, Martin Morovic, Alexandra Bartkova, Matej Murin, Ahmed Gad, Amelie Bonnet-Garnier, Florina Popovska Percinic, Jozef Laurincik

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Michal BencFaculty of Natural Sciences, Constantine the Philosopher University in Nitra, Nabrezie mladeze 91, 94974 Nitra, Slovakia.ORCID 0000-0002-1241-8266
Frantisek StrejcekFaculty of Natural Sciences, Constantine the Philosopher University in Nitra, Nabrezie mladeze 91, 94974 Nitra, Slovakia.
Martin MorovicFaculty of Natural Sciences, Constantine the Philosopher University in Nitra, Nabrezie mladeze 91, 94974 Nitra, Slovakia.
Alexandra BartkovaFaculty of Natural Sciences, Constantine the Philosopher University in Nitra, Nabrezie mladeze 91, 94974 Nitra, Slovakia.ORCID 0000-0001-5221-4025
Matej MurinInstitute of Animal Physiology and Genetics, The Czech Academy of Sciences, 27721 Libechov, Czech Republic.
Ahmed GadInstitute of Animal Physiology and Genetics, The Czech Academy of Sciences, 27721 Libechov, Czech Republic.ORCID 0000-0001-9741-2105
Amelie Bonnet-GarnierUniversité Paris-Saclay, UVSQ, INRAE, BREED, 78350 Jouy-en-Josas, France.
Florina Popovska PercinicFaculty of Veterinary Medicine, St. Cyril and Methodius University in Skopje, 1000 Skopje, North Macedonia.
Jozef LaurincikFaculty of Natural Sciences, Constantine the Philosopher University in Nitra, Nabrezie mladeze 91, 94974 Nitra, Slovakia.
Constantine the Philosopher University in Nitra · SKCzech Academy of Sciences, Institute of Animal Physiology and Genetics · CZÉcole Nationale Vétérinaire d'Alfort · FRSs. Cyril and Methodius University in Skopje · MK

Funding

Agentúra na Podporu Výskumu a Vývoja SK-FR-19-0010Danish Council for Independent Research/Natural Sciences (FNU) 8021-00048BEuropean Community 26220220180FVMS-IPR-02 2020-2090/4Operational Programme Research, Development and Education CZ.02.1.01/0.0/0.0/15_003/0000460Vedecká Grantová Agentúra MŠVVaŠ SR a SAV 1/0001/19Vedecká Grantová Agentúra MŠVVaŠ SR a SAV 1/0167/20
6 · The paper itself

Abstract

The nucleolus is an important nucleus sub-organelle found in almost all eukaryotic cells. On the one hand, it is known as a differentiated active site of ribosome biogenesis in somatic cells, but on the other hand, in fully grown oocytes, zygotes, and early embryos (up to the major embryonic genome activation), it is in the form of a particular homogenous and compact structure called a fibrillar sphere. Nowadays, thanks to recent studies, we know many important functions of this, no doubt, interesting membraneless nucleus sub-organelle involved in oocyte maturation, embryonic genome activation, rRNA synthesis, etc. However, many questions are still unexplained and remain a mystery. Our aim is to create a comprehensive overview of the recent knowledge on the fibrillar sphere and envision how this knowledge could be utilized in further research in the field of biotechnology and nucleolotransfer therapy.

Indexed as

embryonucleolotransfernucleolusoocytezygote

Identifiers

PMID33918523
PMCPMC8066131
OpenAlexW3146621001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.