Evidence map›Paper›PMID 33918510›Full record

ArticleInternational journal of molecular sciences2021

Structural Investigation and Molecular Modeling Studies of Strobilurin-Based Fungicides Active against the Rice Blast Pathogen

Andrea Kunova, Luca Palazzolo, Fabio Forlani, Giorgia Catinella, Loana Musso, Paolo Cortesi, Ivano Eberini, Andrea Pinto, Sabrina Dallavalle

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Exploration of Novel Scaffolds Targeting CytochromeInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Andrea KunovaDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milan, Italy.ORCID 0000-0002-9210-4792
Luca PalazzoloDepartment of Pharmacological and Biomolecular Sciences (DiSFeB), University of Milan, 20133 Milan, Italy.
Fabio ForlaniDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milan, Italy.ORCID 0000-0001-9405-973X
Giorgia CatinellaDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milan, Italy.ORCID 0000-0002-1887-1272
Loana MussoDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milan, Italy.ORCID 0000-0002-6838-7753
Paolo CortesiDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milan, Italy.
Ivano EberiniDepartment of Pharmacological and Biomolecular Sciences (DiSFeB), University of Milan, 20133 Milan, Italy.
Andrea PintoDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milan, Italy.ORCID 0000-0002-2501-3348
Sabrina DallavalleDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milan, Italy.ORCID 0000-0002-8813-8922
University of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing emergence of fungicide-resistant pathogens requires urgent solutions for crop disease management. Here, we describe a structural investigation of new fungicides obtained by combining strobilurin and succinate dehydrogenase inhibitor pharmacophores. We identified compounds endowed with very good activity against wild-type

Indexed as

AscomycotaDrug Resistance, FungalFungicides, IndustrialMicrobial Sensitivity TestsMolecular Docking SimulationStrobilurinsSuccinate DehydrogenaseFungicides, IndustrialStrobilurinsSuccinate Dehydrogenaseantifungal compoundscrop protectioncytochrome bc1 complexhomology modelingmolecular dockingrice blast

Identifiers

PMID33918510
PMCPMC8038316
OpenAlexW3152055106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.