Evidence map›Paper›PMID 33918457›Full record

ReviewCancers2021

Margin Assessment in Soft Tissue Sarcomas: Review of the Literature.

Andrea Sambri, Emilia Caldari, Michele Fiore, Riccardo Zucchini, Claudio Giannini, Maria Giulia Pirini, Paolo Spinnato, Alberta Cappelli, Davide Maria Donati, Massimiliano De Paolis

Abstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Surgical neurology international · 2026
    Article
  5. Review
  6. Review
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrea SambriAlma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-2099-8547
Emilia CaldariIRCCS Policlinico di Sant'Orsola, 40138 Bologna, Italy.
Michele FioreIRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0003-0546-670X
Riccardo ZucchiniIRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Claudio GianniniIRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Maria Giulia PiriniIRCCS Policlinico di Sant'Orsola, 40138 Bologna, Italy.
Paolo SpinnatoIRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0001-6060-3215
Alberta CappelliIRCCS Policlinico di Sant'Orsola, 40138 Bologna, Italy.
Davide Maria DonatiAlma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.
Massimiliano De PaolisIRCCS Policlinico di Sant'Orsola, 40138 Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adequacy of margins must take into consideration both the resection margin width (quantity) and anatomic barrier (quality). There are several classification schemes for reporting surgical resection margin status for soft tissue sarcomas (STS). Most of the studies regarding treatment outcomes in STS included all histologic grades and histological subtypes, which include infiltrative and non-infiltrative subtypes and are very heterogeneous in terms of both histologic characteristics and treatment modalities (adjuvant treatments or not). This lack of consistency makes it difficult to compare results from study to study. Therefore, there is a great need for evidence-based standardization concerning the width of resection margins. The aim of this narrative review is to provide a comprehensive assessment of the literature on margins, and to highlight the need for a uniform description of the margin status for patients with STS. Patient cases should be discussed at multidisciplinary tumor boards and treatments should be individualized to clinical and demographic characteristics, which must include also a deep knowledge of specific histotypes behaviors, particularly infiltrative ones.

Indexed as

classificationinfiltrativelocal recurrencemarginssoft tissue sarcoma

Identifiers

PMID33918457
PMCPMC8038240

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.