Evidence map›Paper›PMID 33918417›Full record

ArticleNutrients2021

Carrot Supplementation Improves Blood Pressure and Reduces Aortic Root Lesions in an Atherosclerosis-Prone Genetic Mouse Model.

Raffaella Soleti, Marine Coué, Charlotte Trenteseaux, Gregory Hilairet, Lionel Fizanne, Fatima Kasbi-Chadli, Patricia Mallegol, Julien Chaigneau, Jerome Boursier, Michel Krempf and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Raffaella SoletiSOPAM, U1063, Inserm, SFR Interactions Cellulaires et Applications Thérapeutiques Université D'Angers, 49 933 Angers, France.ORCID 0000-0002-0271-0490
Marine CouéUMR 1280 Physiopathologie des Adaptations Nutritionnelles (PhAN), INRAE, Université de Nantes, 44 093 Nantes, France.ORCID 0000-0001-8435-7143
Charlotte TrenteseauxUMR 1280 Physiopathologie des Adaptations Nutritionnelles (PhAN), INRAE, Université de Nantes, 44 093 Nantes, France.
Gregory HilairetSOPAM, U1063, Inserm, SFR Interactions Cellulaires et Applications Thérapeutiques Université D'Angers, 49 933 Angers, France.
Lionel FizanneEA 3859, Hémodynamique, Interaction Fibrose et Invasivité Tumorales Hépatiques (HIFIH), Université d'Angers, 49 933 Angers, France.
Fatima Kasbi-ChadliUMR 1280 Physiopathologie des Adaptations Nutritionnelles (PhAN), INRAE, Université de Nantes, 44 093 Nantes, France.
Patricia MallegolSOPAM, U1063, Inserm, SFR Interactions Cellulaires et Applications Thérapeutiques Université D'Angers, 49 933 Angers, France.
Julien ChaigneauEA 3859, Hémodynamique, Interaction Fibrose et Invasivité Tumorales Hépatiques (HIFIH), Université d'Angers, 49 933 Angers, France.
Jerome BoursierEA 3859, Hémodynamique, Interaction Fibrose et Invasivité Tumorales Hépatiques (HIFIH), Université d'Angers, 49 933 Angers, France.
Michel KrempfUMR 1280 Physiopathologie des Adaptations Nutritionnelles (PhAN), INRAE, Université de Nantes, 44 093 Nantes, France.
Emmanuel GeoffriauInstitut Agro, Université d'Angers, INRAE, IRHS, SFR QUASAV, 49 045 Angers, France.ORCID 0000-0003-4384-3107
Ramaroson AndriantsitohainaSOPAM, U1063, Inserm, SFR Interactions Cellulaires et Applications Thérapeutiques Université D'Angers, 49 933 Angers, France.ORCID 0000-0002-4770-3585
Khadija OuguerramUMR 1280 Physiopathologie des Adaptations Nutritionnelles (PhAN), INRAE, Université de Nantes, 44 093 Nantes, France.
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRInserm · FRUniversité d'Angers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemiological studies have shown that carrot consumption may be associated with a lower risk of developing several metabolic dysfunctions. Our group previously determined that the Bolero (Bo) carrot variety exhibited vascular and hepatic tropism using cellular models of cardiometabolic diseases. The present study evaluated the potential metabolic and cardiovascular protective effect of Bo, grown under two conditions (standard and biotic stress conditions (BoBS)), in apolipoprotein E-knockout (ApoE

Indexed as

Daucus carotaDietary SupplementsAnimalsAortaApolipoproteins EBlood PressureCardiac OutputCardiometabolic Risk FactorsCardiovascular DiseasesCecumDiet, High-FatDisease Models, AnimalLipid PeroxidationLipogenesisLipoproteins, VLDLMiceApolipoproteins ELipoproteins, VLDLPropionatesTriglyceridesApoE−/−atherosclerosiscarrot supplementationhemodynamic parameterhigh fat diet

Identifiers

PMID33918417
PMCPMC8065932
OpenAlexW3141025187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.