Evidence map›Paper›PMID 33918347›Full record

ArticleJournal of clinical medicine2021

Identifying Glycemic Variability in Diabetes Patient Cohorts and Evaluating Disease Outcomes.

Martin C Nwadiugwu, Dhundy R Bastola, Christian Haas, Doug Russell

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martin C NwadiugwuDepartment of Biomedical Informatics, University of Nebraska at Omaha, Omaha, NE 68182, USA.ORCID 0000-0001-6788-8305
Dhundy R BastolaDepartment of Biomedical Informatics, University of Nebraska at Omaha, Omaha, NE 68182, USA.
Christian HaasDepartment of Information Systems and Quantitative Analysis, University of Nebraska at Omaha, Omaha, NE 68182, USA.
Doug RussellThink Whole Person Healthcare, Omaha, NE 68106, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycemic variability (GV) is an obstacle to effective blood glucose control and an autonomous risk factor for diabetes complications. We, therefore, explored sample data of patients with diabetes mellitus who maintained better amplitude of glycemic fluctuations and compared their disease outcomes with groups having poor control. A retrospective study was conducted using electronic data of patients having hemoglobin A1C (HbA1c) values with five recent time points from Think Whole Person Healthcare (TWPH). The control variability grid analysis (CVGA) plot and coefficient of variability (CV) were used to identify and cluster glycemic fluctuation. We selected important variables using LASSO. Chi-Square, Fisher's exact test, Bonferroni chi-Square adjusted residual analysis, and multivariate Kruskal-Wallis tests were used to evaluate eventual disease outcomes. Patients with very high CV were strongly associated (

Indexed as

comorbiditydiabetes mellitusglycemic variabilityHbA1c

Identifiers

PMID33918347
PMCPMC8038275

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.