Evidence map›Paper›PMID 33918305›Full record

ReviewJournal of clinical medicine2021

Cutaneous Mastocytosis in Childhood-Update from the Literature.

Florica Sandru, Răzvan-Cosmin Petca, Monica Costescu, Mihai Cristian Dumitrașcu, Adelina Popa, Aida Petca, Raluca-Gabriela Miulescu

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Diffuse Cutaneous Mastocytosis: A Current Understanding of a Rare Disease.International journal of molecular sciences · 2024
    Review
  8. Review
  9. Review
  10. Review
  11. Cutaneous Mastocytosis in Childhood: An Update from the Literature.Journal of clinical practice and research · 2023
    Review
  12. The many faces of pediatric urticaria.Frontiers in allergy · 2023
    Review
  13. Article
  14. Mastocytosis and Mast Cell Activation Disorders: Clearing the Air.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Florica Sandru"Carol Davila" University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Răzvan-Cosmin Petca"Carol Davila" University of Medicine and Pharmacy, 030167 Bucharest, Romania.ORCID 0000-0003-4496-1535
Monica Costescu"Carol Davila" University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Mihai Cristian Dumitrașcu"Carol Davila" University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Adelina PopaDepartment of Dermatology, Elias University Emergency Hospital, 0611461 Bucharest, Romania.
Aida Petca"Carol Davila" University of Medicine and Pharmacy, 030167 Bucharest, Romania.ORCID 0000-0002-4890-0978
Raluca-Gabriela Miulescu"Carol Davila" University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mastocytosis (M) represents a systemic pathology characterized by increased accumulation and clonal proliferation of mast cells in the skin and/or different organs. Broadly, M is classified into two categories: Cutaneous mastocytosis (CM) and systemic mastocytosis (SM). In children, CM is the most frequent form. Unfortunately, pathogenesis is still unclear. It is thought that genetic factors are involved, but further studies are necessary. As for features of CM, the lesions differ in clinical forms. The most important fact is evaluating a pediatric patient with CM. It must comprise laboratory exams (with baseline dosing of total serum tryptase), a skin biopsy (with a pathological exam and, if the diagnosis is unclear, immunohistochemical tests), and a complete clinical evaluation. It is also defining to distinguish between CM and other diseases with cutaneous involvement. As for the management of CM in children, the first intervention implies eliminating trigger factors. The available cures are oral H1 and/or H2 antihistamines, oral cromolyn sodium, oral methoxypsoralen therapy with long-wave psoralen plus ultraviolet A radiation, potent dermatocorticoid, and calcineurin inhibitors. In children, the prognosis of CM is excellent, especially if the disease's onset is in the first or second years of life.

Indexed as

antihistamineschildrencromolyn sodiumcutaneous mastocytosismastocytosisPUVAsystemic mastocytosisurticaria pigmentosa

Identifiers

PMID33918305
PMCPMC8038134
OpenAlexW3141710827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.