Evidence map›Paper›PMID 33918220›Full record

ReviewLife (Basel, Switzerland)2021

Loss of p16: A Bouncer of the Immunological Surveillance?

Kelly E Leon, Naveen Kumar Tangudu, Katherine M Aird, Raquel Buj

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. N6-Methyladenosine Methylation of mRNA in Cell Senescence.Cellular and molecular neurobiology · 2023
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kelly E LeonUPMC Hillman Cancer Center, Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.ORCID 0000-0002-5279-862X
Naveen Kumar TanguduUPMC Hillman Cancer Center, Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Katherine M AirdUPMC Hillman Cancer Center, Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Raquel BujUPMC Hillman Cancer Center, Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.ORCID 0000-0002-8355-6666
UPMC Hillman Cancer Center · US

Funding

Investigating p16 Loss in Pro-tumorigenic MetabolismR37CA240625 · NCI · WISTAR INSTITUTE · PI AIRD, KATHERINE MARIE · 2020 to 2025
$2.6M
Metabolic-Epigenetic regulation of the senescence microenvironment in ovarian cancerF31CA250366 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LEON, KELLY ESME · 2020 to 2021
$45k
NCI NIH HHS F31 CA250366NCI NIH HHS F31CA250366NCI NIH HHS R37 CA240625NCI NIH HHS R37CA240625
6 · The paper itself

Abstract

p16

Indexed as

cell-cyclechemotherapy resistancemelanomapancreatic adenocarcinomasenescencesenescence-associated secretory phenotype (SASP)tumor infiltration

Identifiers

PMID33918220
PMCPMC8065641
OpenAlexW3146752451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.