Evidence map›Paper›PMID 33918189›Full record

ReviewMicromachines2021

Public-Health-Driven Microfluidic Technologies: From Separation to Detection.

Xiangzhi Zhang, Xiawei Xu, Jing Wang, Chengbo Wang, Yuying Yan, Aiguo Wu, Yong Ren

Abstract readReview
In one paragraph

Review in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiangzhi ZhangResearch Group for Fluids and Thermal Engineering, University of Nottingham Ningbo China, Ningbo 315100, China.
Xiawei XuDepartment of Mechanical, Materials and Manufacturing Engineering, University of Nottingham Ningbo China, Ningbo 315100, China.
Jing WangDepartment of Electrical and Electronic Engineering, University of Nottingham Ningbo China, Ningbo 315100, China.ORCID 0000-0001-7735-8682
Chengbo WangDepartment of Electrical and Electronic Engineering, University of Nottingham Ningbo China, Ningbo 315100, China.
Yuying YanResearch Group for Fluids and Thermal Engineering, University of Nottingham, Nottingham NG7 2RD, UK.
Aiguo WuCixi Institute of Biomedical Engineering, CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.ORCID 0000-0001-7200-8923
Yong RenResearch Group for Fluids and Thermal Engineering, University of Nottingham Ningbo China, Ningbo 315100, China.ORCID 0000-0001-6865-5861

Funding

EU ThermaSMART H2020-MSCA-RISE (778104)National Natural Science Foundation of China NSFC31971292Ningbo Science and Technology Bureau under Service Industry Science & Technology Programme 2019F1030Zhejiang Provincial Key Laboratory Programme 2020E10018Zhejiang Provincial Natural Science Foundation of China LQ19F050003Zhejiang Provincial Natural Science Foundation of China LY19E060001
6 · The paper itself

Abstract

Separation and detection are ubiquitous in our daily life and they are two of the most important steps toward practical biomedical diagnostics and industrial applications. A deep understanding of working principles and examples of separation and detection enables a plethora of applications from blood test and air/water quality monitoring to food safety and biosecurity; none of which are irrelevant to public health. Microfluidics can separate and detect various particles/aerosols as well as cells/viruses in a cost-effective and easy-to-operate manner. There are a number of papers reviewing microfluidic separation and detection, but to the best of our knowledge, the two topics are normally reviewed separately. In fact, these two themes are closely related with each other from the perspectives of public health: understanding separation or sorting technique will lead to the development of new detection methods, thereby providing new paths to guide the separation routes. Therefore, the purpose of this review paper is two-fold: reporting the latest developments in the application of microfluidics for separation and outlining the emerging research in microfluidic detection. The dominating microfluidics-based passive separation methods and detection methods are discussed, along with the future perspectives and challenges being discussed. Our work inspires novel development of separation and detection methods for the benefits of public health.

Indexed as

detectionlab-on-a-chipmicrofluidic systempublic healthseparation

Identifiers

PMID33918189
PMCPMC8066776

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.