ArticleJournal of clinical medicine2021
Delayed Improvement of Depression and Anxiety after Transcatheter Aortic Valve Implantation (TAVI) in Stages of Extended Extra-Valvular Cardiac Damage.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Prevalence and course of depression in older people with aortic stenosis undergoing transcatheter aortic valve implantation - a systematic review and meta-analysis.BMC geriatrics · 2025Pooled it
- The Staging of Cardiac Damage for Aortic Stenosis: A Review.Structural heart : the journal of the Heart Team · 2025Review
- Multiparametric Outcome Assessment After Transcatheter Aortic Valve Implantation-A Systematic Review.Journal of clinical medicine · 2025Review
- Depression in Cardiac Patients Is a Major Cardiovascular Event Risk Factor: A 12-Month Observational Study.Journal of clinical medicine · 2024Article
- The Association between Aortic Valve Stenosis and a Subsequent Diagnosis of Depression in Germany.Journal of clinical medicine · 2024Article
- Quality of life in patients with transcatheter aortic valve implantation: an analysis from the INTERVENT project.Frontiers in cardiovascular medicine · 2023Article
- The Trajectory of Nutritional Status and Physical Activity before and after Transcatheter Aortic Valve Implantation.Nutrients · 2022Article
- Quality of Life and Depressive Symptoms in Transcatheter Aortic Valve Implementation Patients-A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2022Article
- Mental health and transcatheter aortic valve replacement: A scoping systematic review.General hospital psychiatryArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepression and anxiety are frequently occurring and likely to be linked to the severity of cardiac diseases like aortic stenosis (AS). This seems to be of interest since a staging classification of extra-valvular cardiac damage in AS has been introduced and shown to be of prognostic relevance.
objectiveThe current study aimed to investigate the frequency of depression and anxiety in association to staging and their dynamics after transcatheter aortic valve implantation (TAVI).
methodsA total number of 224 AS patients undergoing TAVI were classified according to the 2017 staging classification into stage 0 to 4 and further dichotomized into group A (stage 0 to 2) and B (stage 3 and 4). Using the Hospital Anxiety and Depression Scale (HADS-D), patients were assigned to depressive versus non-depressive or anxious versus non-anxious per staging group respectively, and analyzed at baseline, 6 weeks, 6 months and 12 months after TAVI.
resultsAfter dichotomization, 158 patients (70.5%) were assigned to group A and 66 patients (29.5%) to group B. The part showing pathologic values for depression was 25.4% (57/224 patients) in the entire collective, 26.6% (42/158 patients) in group A and 22.7% (15/66 patients) in group B (
conclusionsAlthough of proven prognostic relevance, higher stages of extra-valvular cardiac damage are not associated with higher rates of pre-existing depression or anxiety. The TAVI procedure resulted in a persisting reduction of depression and anxiety in patients showing pathologic values at baseline. Notably, these improvements are timely delayed in higher stages.
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