ReviewPolymers2021
Emerging Biofabrication Techniques: A Review on Natural Polymers for Biomedical Applications.
Review in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed.
- Structure-Function Engineering of Hydrogel-MOF Polymer Composites for Regenerative Wound Dressings with Emerging Antiviral Biointerface Functions.Gels (Basel, Switzerland) · 2026Review
- From Nature to Innovation: Exploring Natural Biopolymers in 3D Bioprinting for Bone Regeneration.ACS omega · 2026Article
- From bone replacement to regeneration. A biomaterials started journey.Materials today. Bio · 2026Review
- Natural Polymers in Tissue Engineering and Regeneration: Material-Cell Mechanotransduction, Biofabrication Strategies, and Clinical Translation.Biomedicines · 2026Review
- Organoid bioprinting to pattern the matrix microenvironment.Current opinion in biomedical engineering · 2025Article
- Tissue Regeneration of Radiation-Induced Skin Damages Using Protein/Polysaccharide-Based Bioengineered Scaffolds and Adipose-Derived Stem Cells: A Review.International journal of molecular sciences · 2025Review
- Biomimetic Three-Dimensional (3D) Scaffolds from Sustainable Biomaterials: Innovative Green Medicine Approach to Bone Regeneration.Journal of functional biomaterials · 2025Review
- Polyhexamethylene Biguanide Nanoparticles Inhibit Biofilm Formation by Mastitis-CausingVeterinary sciences · 2025Article
- A Review of the Development of Biopolymer Hydrogel-Based Scaffold Materials for Drug Delivery and Tissue Engineering Applications.Gels (Basel, Switzerland) · 2025Review
- Polycaprolactone for Hard Tissue Regeneration: Scaffold Design and In Vivo Implications.Bioengineering (Basel, Switzerland) · 2025Review
- 3D-Printed Polymeric Biomaterials for Health Applications.Advanced healthcare materials · 2025Review
- Cysteine Conjugation: An Approach to Obtain Polymers with Enhanced Muco- and Tissue Adhesion.International journal of molecular sciences · 2024Review
- Cartilage Repair: Promise of Adhesive Orthopedic Hydrogels.International journal of molecular sciences · 2024Review
- Biodegradable Natural Hydrogels for Tissue Engineering, Controlled Release, and Soil Remediation.Polymers · 2024Review
- Exploring Protein-Based Carriers in Drug Delivery: A Review.Pharmaceutics · 2024Review
- Fabrication Strategies for Bioceramic Scaffolds in Bone Tissue Engineering with Generative Design Applications.Biomimetics (Basel, Switzerland) · 2024Review
- Review on Electrospray Nanoparticles for Drug Delivery: Exploring Applications.Polymers for advanced technologies · 2024Article
- Review
- 3D printing technology and its combination with nanotechnology in bone tissue engineering.Biomedical engineering letters · 2024Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Natural polymers have been widely used for biomedical applications in recent decades. They offer the advantages of resembling the extracellular matrix of native tissues and retaining biochemical cues and properties necessary to enhance their biocompatibility, so they usually improve the cellular attachment and behavior and avoid immunological reactions. Moreover, they offer a rapid degradability through natural enzymatic or chemical processes. However, natural polymers present poor mechanical strength, which frequently makes the manipulation processes difficult. Recent advances in biofabrication, 3D printing, microfluidics, and cell-electrospinning allow the manufacturing of complex natural polymer matrixes with biophysical and structural properties similar to those of the extracellular matrix. In addition, these techniques offer the possibility of incorporating different cell lines into the fabrication process, a revolutionary strategy broadly explored in recent years to produce cell-laden scaffolds that can better mimic the properties of functional tissues. In this review, the use of 3D printing, microfluidics, and electrospinning approaches has been extensively investigated for the biofabrication of naturally derived polymer scaffolds with encapsulated cells intended for biomedical applications (e.g., cell therapies, bone and dental grafts, cardiovascular or musculoskeletal tissue regeneration, and wound healing).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.