Evidence map›Paper›PMID 33917988›Full record

ArticleToxins2021

Analysis of Multiple Mycotoxins in the Qatari Population and Their Relation to Markers of Oxidative Stress.

Belqes Al-Jaal, Aishah Latiff, Sofia Salama, Huda Mohamed Hussain, Noora Abdulaziz Al-Thani, Noor Al-Naimi, Noof Al-Qasmi, Peter Horvatovich, Morana Jaganjac

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Belqes Al-JaalAnti-Doping Lab Qatar, Sport City Road, Doha P.O. Box 27775, Qatar.
Aishah LatiffSchool of Pharmaceutical Sciences, University of Science Malaysia, Gelugor 11700, Pulau Pinang, Malaysia.
Sofia SalamaAnti-Doping Lab Qatar, Sport City Road, Doha P.O. Box 27775, Qatar.
Huda Mohamed HussainAnti-Doping Lab Qatar, Sport City Road, Doha P.O. Box 27775, Qatar.ORCID 0000-0002-7596-5267
Noora Abdulaziz Al-ThaniAnti-Doping Lab Qatar, Sport City Road, Doha P.O. Box 27775, Qatar.
Noor Al-NaimiAnti-Doping Lab Qatar, Sport City Road, Doha P.O. Box 27775, Qatar.
Noof Al-QasmiAnti-Doping Lab Qatar, Sport City Road, Doha P.O. Box 27775, Qatar.
Peter HorvatovichDepartment of Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV Groningen, The Netherlands.ORCID 0000-0003-2218-1140
Morana JaganjacDivision of Molecular Medicine, Rudjer Boskovic Institute, Bijenicka 54, 10000 Zagreb, Croatia.ORCID 0000-0001-5051-1843
Anti-Doping Laboratory · QARuđer Bošković Institute · HRUniversiti Sains Malaysia · MYUniversity of Groningen · NL

Funding

Qatar National Research Fund NPRP8-1472-3-290
6 · The paper itself

Abstract

Mycotoxins are naturally occurring food toxins worldwide that can cause serious health effects. The measurement of mycotoxin biomarkers in biological fluids is needed to assess individuals' exposure. The aim of this study was to investigate the incidence of mycotoxins in the Qatari population. Serum samples from 412 adults and urinary samples from 559 adults were analyzed for the presence of mycotoxin biomarkers. Multimycotoxin approaches have been applied, using liquid chromatography mass spectrometry methods. Samples were further analyzed for the oxidative stress markers and compared with regard to the incidence of mycotoxins. The presence of mycotoxins was identified in 37% of serum samples and in less than 20% of urine samples. It was found that 88% of positive of the samples were positive for only one mycotoxin, while 12% of positive samples had two or more mycotoxins. Trichothecenes and zearalenone metabolites were most commonly detected mycotoxins, followed by aflatoxins, roquefortine C and mycophenolic acid. The presence of mycotoxins was found to positively correlate with oxidative stress markers. The obtained results illustrate the importance of mycotoxin biomonitoring studies in humans and the need to elucidate the underlying mechanisms of mycotoxin-induced toxicity.

Indexed as

Biological MonitoringFood ContaminationOxidative StressAdultBiomarkersBody BurdenChromatography, High Pressure LiquidDNA DamageFemaleHumansMaleMiddle AgedMycotoxinsQatarSpectrometry, Mass, Electrospray IonizationTandem Mass SpectrometryBiomarkersMycotoxinshuman biomonitoringmycotoxin exposureoxidative stress

Identifiers

PMID33917988
PMCPMC8068385
OpenAlexW3155569919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.