Evidence map›Paper›PMID 33917967›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Candidemia among Iranian Patients with Severe COVID-19 Admitted to ICUs.

Amir Arastehfar, Tahmineh Shaban, Hossein Zarrinfar, Maryam Roudbary, Mona Ghazanfari, Mohammad-Taghi Hedayati, Alireza Sedaghat, Macit Ilkit, Mohammad Javad Najafzadeh, David S Perlin

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 4 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 4 syntheses or guidelines pooled it, 85 citations in OpenAlex.

  1. Pooled it
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  5. Article
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  7. Review
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  10. Inhibitory effect ofIranian journal of microbiology · 2024
    Article
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  15. Article
  16. Health of Saudi Women in the Post-Pandemic Era:International journal of women's health · 2024
    Article
  17. Strain and temperature dependent aggregation ofCell surface (Amsterdam, Netherlands) · 2023
    Article
  18. Article
  19. COVID Associated Invasive Aspergillosis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Amir ArastehfarCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA.
Tahmineh ShabanDepartment of Parasitology and Mycology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 9199-91766, Iran.
Hossein ZarrinfarAllergy Research Center, Mashhad University of Medical Sciences, Mashhad 91766-99199, Iran.ORCID 0000-0002-1449-4668
Maryam RoudbaryDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran 1449614535, Iran.
Mona GhazanfariInvasive Fungi Research Center, Communicable Diseases Research Institute, Mazandaran University of Medical Sciences, Sari 48157-33971, Iran.ORCID 0000-0002-3045-9125
Mohammad-Taghi HedayatiInvasive Fungi Research Center, Communicable Diseases Research Institute, Mazandaran University of Medical Sciences, Sari 48157-33971, Iran.
Alireza SedaghatLung Diseases Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 9137913316, Iran.
Macit IlkitDivision of Mycology, University of Çukurova, Adana 01330, Turkey.ORCID 0000-0002-1174-4182
Mohammad Javad NajafzadehDepartment of Parasitology and Mycology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 9199-91766, Iran.
David S PerlinCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA.
Mashhad University of Medical Sciences · IRHackensack Meridian Health · USMazandaran University of Medical Sciences · IRCukurova University · TRIran University of Medical Sciences · IR

Funding

Deputy of Research of Mashhad University of Medical Sciences 991949National Institutes of Medical Research Development Grant/ Award 982822
6 · The paper itself

Abstract

As a novel risk factor, COVID-19 has led to an increase in the incidence of candidemia and an elevated mortality rate. Despite being of clinical importance, there is a lack of data regarding COVID-19-associated candidemia (CAC) among Iranian patients. Therefore, in this retrospective study, we assessed CAC epidemiology in the intensive care units (ICUs) of two COVID-19 centers in Mashhad, Iran, from early November 2020 to late January 2021. Yeast isolates from patients' blood were identified by 21-plex polymerase chain reaction (PCR) and sequencing, then subjected to antifungal susceptibility testing according to the CLSI M27-A3 protocol. Among 1988 patients with COVID-19 admitted to ICUs, seven had fungemia (7/1988; 0.03%), among whom six had CAC. The mortality of the limited CAC cases was high and greatly exceeded that of patients with COVID-19 but without candidemia (100% (6/6) vs. 22.7% (452/1988)). In total, nine yeast isolates were collected from patients with fungemia: five

Indexed as

Candida albicansCandida glabrataCOVID-19COVID-19-associated candidemiamultidrug resistanceRhodotorula mucilaginosa

Identifiers

PMID33917967
PMCPMC8068363
OpenAlexW3154722708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.