Evidence map›Paper›PMID 33917908›Full record

ArticleFoods (Basel, Switzerland)2021

Antioxidant Properties of Olive Mill Wastewater Polyphenolic Extracts on Human Endothelial and Vascular Smooth Muscle Cells.

Anna Maria Posadino, Annalisa Cossu, Roberta Giordo, Amalia Piscopo, Wael M Abdel-Rahman, Antonio Piga, Gianfranco Pintus

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Olive Mill Wastewater Extract: In Vitro Genotoxicity/Antigenotoxicity Assessment on HepaRG Cells.International journal of environmental research and public health · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Sustainability of the Olive Oil System.Foods (Basel, Switzerland) · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Anna Maria PosadinoDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Annalisa CossuDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Roberta GiordoDepartment of Medical Laboratory Sciences, Institute for Medical Research, College of Health Sciences and Sharjah, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Amalia PiscopoDepartment of AGRARIA, Mediterranean University of Reggio Calabria, 89124 Vito Reggio Calabria, Italy.ORCID 0000-0001-7151-5843
Wael M Abdel-RahmanDepartment of Medical Laboratory Sciences, Institute for Medical Research, College of Health Sciences and Sharjah, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0002-2149-1043
Antonio PigaDepartment of Agricultural Environmental Sciences and Food Biotechnology, University of Sassari, Viale Italia 39, 07100 Sassari, Italy.ORCID 0000-0002-0309-5936
Gianfranco PintusDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-3031-7733
University of Sassari · ITUniversity of Sharjah · AEUniversity of Reggio Calabria · IT

Funding

AGER 2 2016-0105Università degli Studi di Sassari Fondo UNISS di Ateneo per la Ricerca 2020
6 · The paper itself

Abstract

This work aims to analyze the chemical and biological evaluation of two extracts obtained by olive mill wastewater (OMW), an olive oil processing byproduct. The exploitation of OMW is becoming an important aspect of development of the sustainable olive oil industry. Here we chemically and biologically evaluated one liquid (L) and one solid (S) extract obtained by liquid-liquid extraction followed by acidic hydrolysis (LLAC). Chemical characterization of the two extracts indicated that S has higher phenol content than L. Hydroxytyrosol and tyrosol were the more abundant phenols in both OMW extracts, with hydroxytyrosol significantly higher in S as compared to L. Both extracts failed to induce cell death when challenged with endothelial cells and vascular smooth muscle cells in cell viability experiments. On the contrary, the higher extract dosages employed significantly affected cell metabolic activity, as indicated by the MTT tests. Their ability to counteract H

Indexed as

antioxidant activityolive mill wastewatersphenolic extractreactive oxygen speciesvascular cells

Identifiers

PMID33917908
PMCPMC8068214
OpenAlexW3155430615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.