Evidence map›Paper›PMID 33917794›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Correlation of CD47 Expression with Adverse Clinicopathologic Features and an Unfavorable Prognosis in Colorectal Adenocarcinoma.

Hyunsung Kim, Seungyun Jee, Yeseul Kim, Jongmin Sim, Seongsik Bang, Hwang Kyu Son, Hosub Park, Jaekyung Myung, Young Hyeh Ko, Seung Sam Paik

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
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  12. Targeting CD47 for cancer immunotherapy.Journal of hematology & oncology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hyunsung KimDepartment of Pathology, Hanyang University College of Medicine, Seoul 04763, Korea.ORCID 0000-0002-8935-7414
Seungyun JeeDepartment of Pathology, Hanyang University College of Medicine, Seoul 04763, Korea.ORCID 0000-0003-3895-817X
Yeseul KimDepartment of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 25440, Korea.
Jongmin SimDepartment of Pathology, Korea University College of Medicine, Seoul 02841, Korea.
Seongsik BangDepartment of Pathology, Hanyang University College of Medicine, Seoul 04763, Korea.
Hwang Kyu SonDepartment of Pathology, Hanyang University College of Medicine, Seoul 04763, Korea.
Hosub ParkDepartment of Pathology, Hanyang University College of Medicine, Seoul 04763, Korea.
Jaekyung MyungDepartment of Pathology, Hanyang University College of Medicine, Seoul 04763, Korea.
Young Hyeh KoDepartment of Pathology, Hanyang University College of Medicine, Seoul 04763, Korea.
Seung Sam PaikDepartment of Pathology, Hanyang University College of Medicine, Seoul 04763, Korea.
Hanyang University · KRKorea University · KRUlsan College · KR

Funding

Hanyang University HY-2020
6 · The paper itself

Abstract

CD47, a transmembrane protein, is widely overexpressed on the tumor cell surface. However, the prognostic significance of CD47 expression in colorectal adenocarcinoma (CRA) has not yet been clarified. Here, we investigated the clinicopathologic significance of CD47 expression in CRA. CD47 expression was evaluated via immunohistochemical analysis of microarray sections of 328 CRA tissues. CD47 expression was observed in 53 (16.2%) of the 328 CRA tissues, and positive expression was associated with lymphatic invasion (

Indexed as

CD47colorectal adenocarcinomaimmune checkpointsimmunohistochemistryprognosis

Identifiers

PMID33917794
PMCPMC8068136
OpenAlexW3155343305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.