Evidence map›Paper›PMID 33917694›Full record

ReviewMolecules (Basel, Switzerland)2021

Algae-Derived Bioactive Molecules for the Potential Treatment of SARS-CoV-2.

Md Asraful Alam, Roberto Parra-Saldivar, Muhammad Bilal, Chowdhury Alfi Afroze, Md Nasir Ahmed, Hafiz M N Iqbal, Jingliang Xu

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Review
  3. The Ocean's Pharmacy: Health Discoveries in Marine Algae.Molecules (Basel, Switzerland) · 2024
    Review
  4. Review
  5. Review
  6. Article
  7. Marine AlgaMarine drugs · 2022
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Plant lectins as prospective antiviral biomolecules in the search for COVID-19 eradication strategies.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Review
  17. Review
  18. Review
  19. Engineering recombinantly expressed lectin-based antiviral agents.Frontiers in cellular and infection microbiology · 2022
    Article
  20. A contemporary review on the important role ofInformatics in medicine unlocked · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Md Asraful AlamSchool of Chemical Engineering, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0002-9865-6686
Roberto Parra-SaldivarTecnologico de Monterrey, School of Engineering and Sciences, Monterrey 64849, Mexico.ORCID 0000-0002-4958-5797
Muhammad BilalSchool of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.ORCID 0000-0001-5388-3183
Chowdhury Alfi AfrozeDepartment of Biotechnology & Genetic Engineering, University of Development Alternative, Dhaka 1209, Bangladesh.
Md Nasir AhmedBiotechnology & Natural Medicine Division, TechB Nutrigenomics, Dhaka 1209, Bangladesh.ORCID 0000-0002-4863-0402
Hafiz M N IqbalTecnologico de Monterrey, School of Engineering and Sciences, Monterrey 64849, Mexico.ORCID 0000-0003-4855-2720
Jingliang XuSchool of Chemical Engineering, Zhengzhou University, Zhengzhou 450001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recently emerged COVID-19 disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has adversely affected the whole world. As a significant public health threat, it has spread worldwide. Scientists and global health experts are collaborating to find and execute speedy diagnostics, robust and highly effective vaccines, and therapeutic techniques to tackle COVID-19. The ocean is an immense source of biologically active molecules and/or compounds with antiviral-associated biopharmaceutical and immunostimulatory attributes. Some specific algae-derived molecules can be used to produce antibodies and vaccines to treat the COVID-19 disease. Algae have successfully synthesized several metabolites as natural defense compounds that enable them to survive under extreme environments. Several algae-derived bioactive molecules and/or compounds can be used against many diseases, including microbial and viral infections. Moreover, some algae species can also improve immunity and suppress human viral activity. Therefore, they may be recommended for use as a preventive remedy against COVID-19. Considering the above critiques and unique attributes, herein, we aimed to systematically assess algae-derived, biologically active molecules that could be used against this disease by looking at their natural sources, mechanisms of action, and prior pharmacological uses. This review also serves as a starting point for this research area to accelerate the establishment of anti-SARS-CoV-2 bioproducts.

Indexed as

COVID-19 Drug TreatmentAntiviral AgentsCarrageenanChlorophytaCOVID-19HumansLectinsPhaeophyceaePolysaccharidesRhodophytaSARS-CoV-2Antiviral AgentsCarrageenanLectinsPolysaccharidesalgae compoundsantiviral agentbioactive entitiesCOVID-19 treatmentimmunomodulatorypharmacological usestherapeutic aspects

Identifiers

PMID33917694
PMCPMC8068085

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.