Evidence map›Paper›PMID 33917604›Full record

ArticleBiomolecules2021

Co-Therapy of Albendazole and Dexamethasone Reduces Pathological Changes in the Cerebral Parenchyma of Th-1 and Th-2 Dominant Mice Heavily Infected with

Kai-Yuan Jhan, Chien-Ju Cheng, Shih-Ming Jung, Yi-Jen Lai, Kuang-Yao Chen, Lian-Chen Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kai-Yuan JhanGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Chien-Ju ChengDepartment of Parasitology, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Shih-Ming JungDepartment of Pathology, Chang-Gung Memorial Hospital, Chang-Gung Children Hospital at Linkou and Chang-Gung University, Taoyuan 333, Taiwan.
Yi-Jen LaiGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Kuang-Yao ChenDepartment of Parasitology, School of Medicine, China Medical University, Taichung 404, Taiwan.
Lian-Chen WangGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Chang Gung University · TWChina Medical University · TWLinkou Chang Gung Memorial Hospital · TW

Funding

Chang Gung Memorial Hospital, Linkou CMRPD1H0343Chang Gung Memorial Hospital, Linkou CMRPD1H0443Ministry of Science and Technology, Taiwan MOST 109-2320-B-182-032-MY3
6 · The paper itself

Abstract

Administration of albendazole alone was not very suitable for the treatment of cerebral angiostrongyliasis. This study was designed to evaluate the effects of the co-therapy of this drug and dexamethasone in Th-1 and Th-2 dominant mice infected with

Indexed as

AlbendazoleAngiostrongylus cantonensisAnimalsBrainDexamethasoneDisease Models, AnimalDrug Therapy, CombinationMiceMice, Inbred BALB CMice, Inbred C57BLRNASequence Analysis, RNAStrongylida InfectionsTh1 CellsTh2 CellsAlbendazoleDexamethasoneRNAalbendazoleAngiostrongylus cantonensisdexamethasonehistopathologypathological changesRNA-seqscoring

Identifiers

PMID33917604
PMCPMC8067505
OpenAlexW3149167851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.