ReviewBiomedicines2021
Preoperative Localization for Primary Hyperparathyroidism: A Clinical Review.
Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Predicting Failure of Conventional Imaging in Primary Hyperparathyroidism: The Impact of Parathyroid Hormone Levels and Thyroid Nodules.The Eurasian journal of medicine · 2026Article
- Preoperative imaging strategies to optimize surgical treatment in primary hyperparathyroidism (pHPT).BMC surgery · 2026Article
- Indocyanine green fluorescence in parathyroidectomy: enhancing efficiency through real-time adenoma identification.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Data-Driven Surgical Referrals for Primary Hyperparathyroidism and Associated Surgical Outcomes: A Simulation Study.Annals of surgical oncology · 2025Article
- Impact of 18F-choline PET-CT or PET-MRI on surgical strategy in patients with primary hyperparathyroidism.BJS open · 2025Article
- Dynamic 4 dimensional contrast enhanced MRI for localization in primary hyperparathyroidism.Endocrine · 2025Article
- Article
- Meta-Analysis of Image-Based Versus Probe-Based Parathyroid Near-Infrared Autofluorescence.Cureus · 2025Review
- Factors Associated With Successful Parathyroid Adenoma Localisation in Sestamibi Study-Can Change in Serum Calcium Be a Useful Indicator?International journal of endocrinology · 2025Article
- Review
- Diagnostic accuracy of ultrasonography and 99m-Technetium Sestamibi scintigraphy for the preoperative localization of Parathyroid Adenoma keeping histopathological findings as reference standard.Pakistan journal of medical sciences · 2024Article
- Primary hyperparathyroidism: predictors of sporadic multi-gland disease.Endocrine connections · 2024Review
- Characteristics, management and outcomes of primary hyperparathyroidism from 2009 to 2021: a single centre report from South Africa.BMC endocrine disorders · 2024Article
- Ultrasound characteristics of normal parathyroid glands and analysis of the factors affecting their display.BMC medical imaging · 2024Article
- Preoperative identification of small parathyroid adenomas-better done by fluorocholine positron emission tomography/computed tomography.Gland surgery · 2023Article
- Diagnostic Performance of Magnetic Resonance Imaging for Parathyroid Localization of Primary Hyperparathyroidism: A Systematic Review.Diagnostics (Basel, Switzerland) · 2023Review
- The Utility of 4D-CT Imaging in Primary Hyperparathyroidism Management in a Low-Volume Center.Medicina (Kaunas, Lithuania) · 2023Article
- Clinical, Biochemical, and Sonographic Factors Influencing Performance of Parathormone Washout Measurement vs.Journal of clinical medicine · 2023Article
- Approach to the Patient: Management of Parathyroid Diseases Across Pregnancy.The Journal of clinical endocrinology and metabolism · 2023Article
- Multi-modality parathyroid imaging: A shifting paradigm.World journal of radiology · 2023Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
With increasing use of minimally invasive parathyroidectomy (PTx) over traditional bilateral neck exploration in patients with primary hyperparathyroidism (PHPT), accurate preoperative localization has become more important to enable a successful surgical outcome. Traditional imaging techniques such as ultrasound (US) and sestamibi scintigraphy (MIBI) and newer techniques such as parathyroid four-dimension computed tomography (4D-CT), positron emission tomography (PET), and magnetic resonance imaging (MRI) are available for the clinician to detect the diseased gland(s) in the preoperative workup. Invasive parathyroid venous sampling may be useful in certain circumstances such as persistent or recurrent PHPT. We review the diagnostic performance of these imaging modalities in preoperative localization and discuss the advantages and weaknesses of these techniques. US and MIBI are established techniques commonly utilized as first-line modalities. 4D-CT has excellent diagnostic performance and is increasingly performed in first-line setting and as an adjunct to US and MIBI. PET and MRI are emerging adjunct modalities when localization has been equivocal or failed. Since no evidence-based guidelines are yet available for the optimal imaging strategy, clinicians should be familiar with the range and advancement of these techniques. Choice of imaging modality should be individualized to the patient with consideration for efficacy, expertise, and availability of such techniques in clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.