Evidence map›Paper›PMID 33917384›Full record

ArticlePathogens (Basel, Switzerland)2021

Role of the β-Catenin/REG Iα Axis in the Proliferation of Sessile Serrated Adenoma/Polyps Associated with

Heihachiro Nishimura, Hirokazu Fukui, Xuan Wang, Nobuhiko Ebisutani, Takashi Nakanishi, Toshihiko Tomita, Tadayuki Oshima, Seiichi Hirota, Hiroto Miwa

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Detection ofInternational journal of molecular sciences · 2026
    Article
  2. MedComm · 2025
    Review
  3. Article
  4. Regulatory effects of oral microbe on intestinal microbiota and the illness.Frontiers in cellular and infection microbiology · 2023
    Review
  5. A New Comorbidity in Periodontitis:Medicina (Kaunas, Lithuania) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Heihachiro NishimuraDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Hirokazu FukuiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Xuan WangDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Nobuhiko EbisutaniDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine 1-1, Mukogawa, Nishinomiya 663-8501, Japan.ORCID 0000-0002-8850-1816
Takashi NakanishiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Toshihiko TomitaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine 1-1, Mukogawa, Nishinomiya 663-8501, Japan.ORCID 0000-0003-1283-9009
Tadayuki OshimaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine 1-1, Mukogawa, Nishinomiya 663-8501, Japan.ORCID 0000-0001-6949-932X
Seiichi HirotaDepartment of Surgical Pathology, Hyogo College of Medicine 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Hiroto MiwaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Hyogo Medical University · JP

Funding

Grants-in-aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan. 17K09363
6 · The paper itself

Abstract

Although sessile serrated adenoma/polyps (SSA/Ps) may arise through a pathway different from the traditional adenoma-carcinoma sequence, details of SSA/P tumorigenesis still remain unclear.

Indexed as

Fusobacterium nucleatumKi67polypproliferationREGsessile serrated adenomaβ-catenin

Identifiers

PMID33917384
PMCPMC8067346
OpenAlexW3140019811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.