Evidence map›Paper›PMID 33917365›Full record

ArticleMicroorganisms2021

Phage Resistance Is Associated with Decreased Virulence in KPC-Producing

Lucia Henrici De Angelis, Noemi Poerio, Vincenzo Di Pilato, Federica De Santis, Alberto Antonelli, Maria Cristina Thaller, Maurizio Fraziano, Gian Maria Rossolini, Marco Maria D'Andrea

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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  7. Characterization of four novel bacteriophages targeting multi-drug resistantFrontiers in cellular and infection microbiology · 2024
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  12. Fighting MDR-Frontiers in immunology · 2022
    Article
  13. Insertion Mutation ofInfection and drug resistance · 2022
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Lucia Henrici De AngelisDepartment of Medical Biotechnologies, University of Siena, Viale Mario Bracci, 16, 53100 Siena, Italy.
Noemi PoerioDepartment of Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica snc, 00133 Rome, Italy.ORCID 0000-0002-7025-6496
Vincenzo Di PilatoDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Via Benedetto XV, 6, 16126 Genoa, Italy.ORCID 0000-0002-5863-5805
Federica De SantisDepartment of Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica snc, 00133 Rome, Italy.
Alberto AntonelliDepartment of Experimental and Clinical Medicine, University of Florence, Largo Brambilla, 3, 50121 Florence, Italy.ORCID 0000-0003-0295-6877
Maria Cristina ThallerDepartment of Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica snc, 00133 Rome, Italy.ORCID 0000-0003-2788-3563
Maurizio FrazianoDepartment of Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica snc, 00133 Rome, Italy.
Gian Maria RossoliniDepartment of Experimental and Clinical Medicine, University of Florence, Largo Brambilla, 3, 50121 Florence, Italy.
Marco Maria D'AndreaDepartment of Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica snc, 00133 Rome, Italy.ORCID 0000-0003-3187-3210
University of Rome Tor Vergata · ITAzienda Ospedaliero-Universitaria Careggi · ITUniversity of Genoa · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phage therapy is now reconsidered with interest in the treatment of bacterial infections. A major piece of information for this application is the definition of the molecular targets exploited by phages to infect bacteria. Here, the genetic basis of resistance to the lytic phage φBO1E by its susceptible host

Indexed as

capsuleKlebsiella pneumoniaeKlebsiella pneumoniae carbapenemase KPCphagephage resistance mechanismPodoviridaepolysaccharideSequence type 258virulence

Identifiers

PMID33917365
PMCPMC8067426
OpenAlexW3140904578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.