Evidence map›Paper›PMID 33917361›Full record

ReviewMicroorganisms2021

Anti-Classical Swine Fever Virus Strategies.

Jindai Fan, Yingxin Liao, Mengru Zhang, Chenchen Liu, Zhaoyao Li, Yuwan Li, Xiaowen Li, Keke Wu, Lin Yi, Hongxing Ding and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

  1. Virulence · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Molecular breeding of pigs in the genome editing era.Genetics, selection, evolution : GSE · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Structural characterization and adjuvant action ofFrontiers in veterinary science · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jindai FanCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Yingxin LiaoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Mengru ZhangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Chenchen LiuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Zhaoyao LiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Yuwan LiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Xiaowen LiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Keke WuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Lin YiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Hongxing DingCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Mingqiu ZhaoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Shuangqi FanCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Jinding ChenCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
South China Agricultural University · CNKey Laboratory of Guangdong Province · CN

Funding

111 Project D20008Guangdong Major Project of Basic and Applied Basic Research 2020B0301030007Science and Technology Program of Guangzhou, China 201803020005the Key Research Projects of Universities in Guangdong Province 2019KZDXM026the Science and Technology Program of Guangdong, China 2019B020211003
6 · The paper itself

Abstract

Classical swine fever (CSF), caused by CSF virus (CSFV), is a highly contagious swine disease with high morbidity and mortality, which has caused significant economic losses to the pig industry worldwide. Biosecurity measures and vaccination are the main methods for prevention and control of CSF since no specific drug is available for the effective treatment of CSF. Although a series of biosecurity and vaccination strategies have been developed to curb the outbreak events, it is still difficult to eliminate CSF in CSF-endemic and re-emerging areas. Thus, in addition to implementing enhanced biosecurity measures and exploring more effective CSF vaccines, other strategies are also needed for effectively controlling CSF. Currently, more and more research about anti-CSFV strategies was carried out by scientists, because of the great prospects and value of anti-CSFV strategies in the prevention and control of CSF. Additionally, studies on anti-CSFV strategies could be used as a reference for other viruses in the Flaviviridae family, such as hepatitis C virus, dengue virus, and Zika virus. In this review, we aim to summarize the research on anti-CSFV strategies. In detail, host proteins affecting CSFV replication, drug candidates with anti-CSFV effects, and RNA interference (RNAi) targeting CSFV viral genes were mentioned and the possible mechanisms related to anti-CSFV effects were also summarized.

Indexed as

antiviral drugantiviral targetclassical swine fever virushost proteinRNA interference

Identifiers

PMID33917361
PMCPMC8067343
OpenAlexW3148478141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.