Evidence map›Paper›PMID 33917271›Full record

ReviewClinics and practice2021

Malignant Phyllodes Tumor of the Breast: A Practice Review.

Ângelo Bezerra de Souza Fede, Ronaldo Pereira Souza, Mauricio Doi, Marina De Brot, Cynthia Aparecida Bueno de Toledo Osorio, Guilherme Rocha Melo Gondim, Jose Claudio Casali-da-Rocha, Rima Jbili, Almir Galvao Vieira Bitencourt, Juliana Alves de Souza and 3 more

Abstract readReview
In one paragraph

Review in Clinics and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Review
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  13. IntragenicCancers · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ângelo Bezerra de Souza FedeDepartment of Medical Oncology, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.
Ronaldo Pereira SouzaDepartment of Medical Oncology, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.
Mauricio DoiDepartment of Breast Surgery, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.
Marina De BrotDepartment of Anatomic Pathology A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.ORCID 0000-0002-2677-8043
Cynthia Aparecida Bueno de Toledo OsorioDepartment of Anatomic Pathology A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.
Guilherme Rocha Melo GondimDepartment of Radiation Oncology, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.ORCID 0000-0002-1628-0786
Jose Claudio Casali-da-RochaDepartment of Oncogenetics, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.ORCID 0000-0002-1838-2153
Rima JbiliDepartment of Oncogenetics, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.
Almir Galvao Vieira BitencourtDepartment of Imaging, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.ORCID 0000-0003-0192-9885
Juliana Alves de SouzaDepartment of Imaging, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.ORCID 0000-0003-4694-8190
Rafael Caparica BittonInstitut Jules Bordet, Université Libre de Bruxelles (U.L.B.), 1050 Brussels, Belgium.
Fabiana Baroni Alves MakdissiDepartment of Breast Surgery, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.ORCID 0000-0002-4442-0870
Solange Moraes SanchesDepartment of Medical Oncology, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPhyllodes tumor (PT) of the breast, particularly malignant phyllodes tumor (mPT), is a rare fibroepithelial neoplasm. A complex diagnosis is based on pathologic, radiologic, and clinical findings, with controversies about what is the best therapeutic strategy.

objectiveOur objective was to provide an overview of the clinical, pathologic, and therapeutic aspects of this rare tumor.

conclusionsmPT is a rare presentation of breast cancer and a challenge in clinical practice. A multidisciplinary approach should take into account some aspects like pathogenic mutations and hereditary syndromes. Oncologic surgery is the fundamental approach, and the use of adjuvant therapies is still controversial due to the lack of clinical trials. Treatment recommendations should be individualized according to patient risk and preferences. Prospective studies are fundamental to clarifying the best treatment for these tumors.

Indexed as

breast cancerfibroepithelial neoplasmMalignant phyllodes tumor

Identifiers

PMID33917271
PMCPMC8167791

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.