Evidence map›Paper›PMID 33917230›Full record

ReviewCancers2021

Treatment Strategies for ARID1A-Deficient Ovarian Clear Cell Carcinoma.

Kazuaki Takahashi, Masataka Takenaka, Aikou Okamoto, David D L Bowtell, Takashi Kohno

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 52 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Cancers · 2024
    Article
  11. Article
  12. Review
  13. SMARCA4 loss irrelevant forGynecologic oncology reports · 2023
    Article
  14. Article
  15. Developments in Genetics: Better Management of Ovarian Cancer Patients.International journal of molecular sciences · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Kazuaki TakahashiDepartment of Obstetrics and Gynecology, Jikei University School of Medicine, Tokyo 105-8461, Japan.
Masataka TakenakaDepartment of Obstetrics and Gynecology, Jikei University School of Medicine, Tokyo 105-8461, Japan.
Aikou OkamotoDepartment of Obstetrics and Gynecology, Jikei University School of Medicine, Tokyo 105-8461, Japan.
David D L BowtellPeter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
Takashi KohnoDivision of Genome Biology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
Jikei University School of Medicine · JPNational Cancer Centre Japan · JPPeter MacCallum Cancer Centre · AU

Funding

Japan Agency for Medical Research and Development JP20ck0106402
6 · The paper itself

Abstract

Ovarian clear cell carcinoma (OCCC) is a histological subtype of ovarian cancer that is more frequent in Asian countries (~25% of ovarian cancers) than in US/European countries (less than 10%). OCCC is refractory to conventional platinum-based chemotherapy, which is effective against high-grade serous carcinoma (HGSC), a major histological subtype of ovarian cancer. Notably, deleterious mutations in SWI/SNF chromatin remodeling genes, such as

Indexed as

ARID1Agemcitabinemolecular targeted therapyovarian clear cell carcinomaprecision medicinesynthetic lethality

Identifiers

PMID33917230
PMCPMC8068058
OpenAlexW3148840041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.