ArticleJournal of clinical medicine2021
Depression Associated with Reduced Heart Rate Variability Predicts Outcome in Adult Congenital Heart Disease.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Meta-analysis on inflammation and autonomic nervous system of coronary heart disease combined with depression.BMJ open · 2024Pooled it
- A Clinically Oriented Framework for Real-Time Heart Rate Variability Analysis: A Novel Approach To Personalized and Robust Monitoring.Journal of medical systems · 2026Article
- [Traumatic childhood experiences and cardiovascular health using the example of adults with congenital heart disease].Der Nervenarzt · 2026Article
- Age moderates change in disease-related stress among congenital heart disease survivors: a 6-year follow-up.European journal of cardiovascular nursing · 2024Article
- Preprocedural Anxiety in Adults With Congenital Heart Disease: The PANIC Study.JACC. Advances · 2023Article
- Impact of relationship status on psychological parameters in adults with congenital heart disease.Frontiers in psychiatry · 2023Article
- Diversity of Hemodynamic Reactive Profiles across Persons-Psychosocial Implications for Personalized Medicine.Journal of clinical medicine · 2022Article
- Heart Rate Fractality Disruption as a Footprint of Subthreshold Depressive Symptoms in a Healthy Population.Clinical neuropsychiatry · 2022Article
- Impact of COVID-19 on Medical Supply in Adults With Congenital Heart Disease.Frontiers in psychiatry · 2022Article
- Psychological and Psychopharmacological Interventions in Psychocardiology.Frontiers in psychiatry · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In adult congenital heart disease (ACHD), major depressive disorder (MDD) represents a frequent comorbidity. In non-CHD, adverse outcome is predicted by MDD and heart rate variability (HRV), whereas in ACHD their prognostic relevance is unknown. We prospectively evaluated 171 patients (age 35.6 ± 11.4 years; male 42.7%, mean observation time 54.7 ± 14.9 months). Binary regression analysis calculated the association between MDD and HRV. Cox proportional survival analysis estimated their impact on decompensated heart failure and all-cause mortality (HF/death), supraventricular and ventricular tachycardia (SVT/VT), and hospitalization due to unexpected cardiac causes. Exclusively MDD with moderate/severe symptoms showed significantly lower HRV as derived from frequency-domain analysis (Symindex) (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.