Evidence map›Paper›PMID 33916950›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Salivary Biomarkers and Oral Health in Liver Transplant Recipients, with an Emphasis on Diabetes.

Annika Emilia Norrman, Taina Tervahartiala, Ella Sahlberg, Timo Sorsa, Hellevi Ruokonen, Lisa Grönroos, Jukka H Meurman, Helena Isoniemi, Arno Nordin, Fredrik Åberg and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Microbiome in Periodontitis and Diabetes.Frontiers in oral health · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Annika Emilia NorrmanDepartment of Oral and Maxillofacial Diseases, Helsinki University Hospital, University of Helsinki, P.O. Box 220, 00100 Helsinki, Finland.ORCID 0000-0002-0575-6494
Taina TervahartialaDepartment of Oral and Maxillofacial Diseases, Helsinki University Hospital, University of Helsinki, P.O. Box 220, 00100 Helsinki, Finland.ORCID 0000-0001-8817-896X
Ella SahlbergDepartment of Oral and Maxillofacial Diseases, University of Helsinki, 00100 Helsinki, Finland.
Timo SorsaDepartment of Oral and Maxillofacial Diseases, Helsinki University Hospital, University of Helsinki, P.O. Box 220, 00100 Helsinki, Finland.
Hellevi RuokonenDepartment of Oral and Maxillofacial Diseases, Helsinki University Hospital, University of Helsinki, P.O. Box 220, 00100 Helsinki, Finland.
Lisa GrönroosDepartment of Oral and Maxillofacial Diseases, Helsinki University Hospital, University of Helsinki, P.O. Box 220, 00100 Helsinki, Finland.
Jukka H MeurmanDepartment of Oral and Maxillofacial Diseases, Helsinki University Hospital, University of Helsinki, P.O. Box 220, 00100 Helsinki, Finland.ORCID 0000-0001-6003-4948
Helena IsoniemiDepartment of Transplantation and Liver Surgery, Helsinki University Hospital, University of Helsinki, P.O. Box 372, 00100 Helsinki, Finland.
Arno NordinDepartment of Transplantation and Liver Surgery, Helsinki University Hospital, University of Helsinki, P.O. Box 372, 00100 Helsinki, Finland.
Fredrik ÅbergDepartment of Transplantation and Liver Surgery, Helsinki University Hospital, University of Helsinki, P.O. Box 372, 00100 Helsinki, Finland.
Jaana Helenius-HietalaDepartment of Oral and Maxillofacial Diseases, Helsinki University Hospital, University of Helsinki, P.O. Box 220, 00100 Helsinki, Finland.ORCID 0000-0001-8843-0272
University of Helsinki · FI

Funding

Helsingin ja Uudenmaan Sairaanhoitopiiri T1020Y001Helsingin ja Uudenmaan Sairaanhoitopiiri TYH2016251Helsingin ja Uudenmaan Sairaanhoitopiiri TYH2017251Helsingin ja Uudenmaan Sairaanhoitopiiri TYH2018229Helsingin ja Uudenmaan Sairaanhoitopiiri TYH2019319Helsingin ja Uudenmaan Sairaanhoitopiiri Y1014SL018Helsingin ja Uudenmaan Sairaanhoitopiiri Y1014SULE1Helsingin ja Uudenmaan Sairaanhoitopiiri Y101SL017Helsingin ja Uudenmaan Sairaanhoitopiiri Y1149SUL22Karolinska InstitutetSuomen Naishammaslääkärit r.y.
6 · The paper itself

Abstract

Salivary biomarkers have been linked to various systemic diseases. We examined the association between salivary biomarkers, periodontal health, and microbial burden in liver transplant (LT) recipients with and without diabetes, after transplantation. We hypothesized that diabetic recipients would exhibit impaired parameters. This study included 84 adults who received an LT between 2000 and 2006 in Finland. Dental treatment preceded transplantation. The recipients were re-examined, on average, six years later. We evaluated a battery of salivary biomarkers, microbiota, and subjective oral symptoms. Periodontal health was assessed, and immunosuppressive treatments were recorded. Recipients with impaired periodontal health showed higher matrix metalloproteinase-8 (MMP-8) levels (

Indexed as

liver diseaseoral infectionsperiodontitissalivasalivary biomarkersteeth

Identifiers

PMID33916950
PMCPMC8067605
OpenAlexW3148369673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.