ArticleAntibiotics (Basel, Switzerland)2021
Increase and Change in the Pattern of Antibiotic Use in Serbia (2010-2019).
Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- A comprehensive descriptive, predictive, and prescriptive analysis of antibiotic products' demand pre-, amid, and post-COVID-19 in Iran.Scientific reports · 2025Article
- Increased Antimicrobial Consumption, Isolation Rate, and Resistance Profiles of Multi-Drug ResistantAntibiotics (Basel, Switzerland) · 2025Article
- Antimicrobial Use and Awareness of Antimicrobial Resistance in the Livestock Sector in the Western Balkans.Antibiotics (Basel, Switzerland) · 2025Article
- Sales of Veterinary Antibiotics in Serbia: Identification of Problem Areas Using Standardized Metrics.Animals : an open access journal from MDPI · 2024Article
- Antimicrobial utilization and resistance in Pseudomonas aeruginosa using segmented regression analysis: a comparative study between Serbia and eight European Countries.International journal of clinical pharmacy · 2023Article
- Incremental costs of hospital-acquired infections in COVID-19 patients in an adult intensive care unit of a tertiary hospital from a low-resource setting.Antimicrobial resistance and infection control · 2023Article
- Serotype distribution, antimicrobial susceptibility and molecular epidemiology of invasiveFrontiers in microbiology · 2023Article
- Analysis of antibiotic use patterns in Danish hospitals 2015-2021 using an adapted version of the who aware classification.BMJ open quality · 2022Article
- Association between Antibiotic Use and Hospital-OnsetAntibiotics (Basel, Switzerland) · 2022Article
- Microbiology of Healthcare-Associated Infections: Results of a Fourth National Point Prevalence Survey in Serbia.Antibiotics (Basel, Switzerland) · 2022Article
- Impact and Value of Hospital Antibiotic Stewardship: Retrospective Pre-COVID-19-Pandemic Analysis.Journal of clinical medicine · 2022Article
- Antibiotic (Mis)Use in COVID-19 Patients before and after Admission to a Tertiary Hospital in Serbia.Antibiotics (Basel, Switzerland) · 2022Article
- Antimicrobial Use in Hospitalised Patients with COVID-19: An International Multicentre Point-Prevalence Study.Antibiotics (Basel, Switzerland) · 2022Article
- The Overlooked Issue of Outpatient Combination Antibiotic Prescribing in Low- and Middle-Income Countries: An Example from Syria.Antibiotics (Basel, Switzerland) · 2022Article
- Farm Animal Veterinarians' Knowledge and Attitudes toward Antimicrobial Resistance and Antimicrobial Use in the Republic of Serbia.Antibiotics (Basel, Switzerland) · 2022Article
- Antibiotic consumption by Access, Watch and Reserve index in public sector of Limpopo province, South Africa: 2014-2018.Southern African journal of infectious diseases · 2022Article
- The Impact of COVID-19 on the Profile of Hospital-Acquired Infections in Adult Intensive Care Units.Antibiotics (Basel, Switzerland) · 2021Article
Corrections and comments
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8 authors.
Funding
Abstract
The aim of this study was to determine and describe trends in antibiotics utilization in Serbia over a ten-year period. Data were retrieved from publicly available annual reports (2010-2019). The results were expressed as Defined Daily Dose (DDD) per 1000 inhabitants per day (DID). All calculations were performed using the DDD values for the 2020 Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) version for each year of the study, to account for the DDD changes during the study period. Antibiotics were classified using the WHO Access, Watch, Reserve (AWaRe) classification. Total utilization of antibacterials for systemic use increased from 17.25 DID in 2010 to 28.65 DID in 2019. A statistically significant increasing trend in the use of the Watch category antibiotics was observed. A tendency towards use of broad-spectrum antibiotics, apparent by a statistically significant increase in the rate of utilization of broad-spectrum macrolides, quinolones and third-generation cephalosporins vs. narrow-spectrum ones, as well as a significant increasing trend in the use of quinolones was identified. Total antibiotic utilization was found to be well above the European average. Several specific problem areas were identified, which requires further efforts to improve antibiotic prescribing. The present study provides the information needed to facilitate antibiotic stewardship in Serbia further and proposes specific interventions to optimize antibiotic use in Serbia.
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