Evidence map›Paper›PMID 33916877›Full record

Trial reportNutrients2021

Urinary Medium-Chained Acyl-Carnitines Sign High Caloric Intake whereas Short-Chained Acyl-Carnitines Sign High -Protein Diet within a High-Fat, Hypercaloric Diet in a Randomized Crossover Design Dietary Trial.

Nadezda V Khodorova, Annemarie Rietman, Douglas N Rutledge, Jessica Schwarz, Julien Piedcoq, Serge Pilard, Els Siebelink, Frans J Kok, Daniel Tomé, Marco Mensink and 1 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Nadezda V KhodorovaAgroParisTech, Université Paris-Saclay, INRAE, UMR PNCA, 75005 Paris, France.
Annemarie RietmanDivision of Human Nutrition & Health, Wageningen University, NL-6703 HD Wageningen, The Netherlands.
Douglas N RutledgeAgroParisTech, Université Paris-Saclay, INRAE, UMR SayFood, 91300 Massy, France.ORCID 0000-0001-5634-0766
Jessica SchwarzDivision of Human Nutrition & Health, Wageningen University, NL-6703 HD Wageningen, The Netherlands.ORCID 0000-0002-2594-2200
Julien PiedcoqAgroParisTech, Université Paris-Saclay, INRAE, UMR PNCA, 75005 Paris, France.
Serge PilardPlateforme Analytique, Université de Picardie Jules Verne, 80039 Amiens, France.ORCID 0000-0002-9167-526X
Els SiebelinkDivision of Human Nutrition & Health, Wageningen University, NL-6703 HD Wageningen, The Netherlands.
Frans J KokDivision of Human Nutrition & Health, Wageningen University, NL-6703 HD Wageningen, The Netherlands.
Daniel ToméAgroParisTech, Université Paris-Saclay, INRAE, UMR PNCA, 75005 Paris, France.ORCID 0000-0003-3866-4884
Marco MensinkDivision of Human Nutrition & Health, Wageningen University, NL-6703 HD Wageningen, The Netherlands.ORCID 0000-0002-9725-5709
Dalila Azzout-MarnicheAgroParisTech, Université Paris-Saclay, INRAE, UMR PNCA, 75005 Paris, France.ORCID 0000-0001-8397-9143
AgroParisTech · FRWageningen University & Research · NLUniversité de Picardie Jules Verne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The western dietary pattern is known for its frequent meals rich in saturated fat and protein, resulting in a postprandial state for a large part of the day. Therefore, our aim was to investigate the postprandial glucose and lipid metabolism in response to high (HP) or normal (NP) protein, high-fat hypercaloric diet and to identify early biomarkers of protein intake and hepatic lipid accumulation. In a crossover design, 17 healthy subjects were randomly assigned to consume a HP or NP hypercaloric diet for two weeks. In parallel, a control group (CD;

Indexed as

AdultBiomarkersCarnitineCross-Over StudiesDietary FatsDietary ProteinsDiet, High-FatDiet, High-ProteinDiet, WesternEnergy IntakeFemaleGlucoseHealthy VolunteersHumansLipid MetabolismLiveracylcarnitineBiomarkersCarnitineDietary FatsDietary ProteinsGlucosedietary proteinglucose metabolismlipid metabolismmedium chain acyl-carnitineplasma metabolomicspostprandial responseshort chain acyl-carnitineurinary metabolomics

Identifiers

PMID33916877
PMCPMC8066704
OpenAlexW3139878524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.