Evidence map›Paper›PMID 33916826›Full record

ArticleCells2021

Lysine 53 Acetylation of Cytochrome

Viktoriia Bazylianska, Hasini A Kalpage, Junmei Wan, Asmita Vaishnav, Gargi Mahapatra, Alice A Turner, Dipanwita Dutta Chowdhury, Katherine Kim, Paul T Morse, Icksoo Lee and 8 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. CytochromeSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Review
  7. Article
  8. CytochromeiScience · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. De novo sequencing and construction of a unique antibody for the recognition of alternative conformations of cytochromeProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Review
  20. Frontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 3 countries.

Viktoriia BazylianskaCenter for Molecular Medicine and Genetics, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Hasini A KalpageCenter for Molecular Medicine and Genetics, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Junmei WanCenter for Molecular Medicine and Genetics, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Asmita VaishnavDepartment of Biochemistry, Microbiology, and Immunology, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Gargi MahapatraCenter for Molecular Medicine and Genetics, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Alice A TurnerCenter for Molecular Medicine and Genetics, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Dipanwita Dutta ChowdhuryDepartment of Biochemistry, Microbiology, and Immunology, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Katherine KimCenter for Molecular Medicine and Genetics, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Paul T MorseCenter for Molecular Medicine and Genetics, School of Medicine, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0003-1530-1466
Icksoo LeeCenter for Molecular Medicine and Genetics, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Joseph S BrunzelleLife Sciences Collaborative Access Team, Center for Synchrotron Research, Northwestern University, Argonne, IL 60439, USA.
Lisa PolinDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA.
Prabal SubediMedical Proteomics/Bioanalytics-Center, Ruhr-University Bochum, 44789 Bochum, Germany.
Elisabeth I HeathDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA.
Izabela PodgorskiDepartment of Pharmacology, Wayne State University, Detroit, MI 48201, USA.
Katrin MarcusMedical Proteomics/Bioanalytics-Center, Ruhr-University Bochum, 44789 Bochum, Germany.ORCID 0000-0002-3313-8845
Brian F P EdwardsDepartment of Biochemistry, Microbiology, and Immunology, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Maik HüttemannCenter for Molecular Medicine and Genetics, School of Medicine, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0001-6310-7081
Wayne State University · USRuhr University Bochum · DENorthwestern University · US

Funding

Tissue/InformaticsP50CA186786 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ganesh S Palapattu · 2014 to 2026
$27.6M
Control of Cell Respiration and Apoptosis by Phosphorylation of Cytochrome cR01GM116807 · NIGMS · WAYNE STATE UNIVERSITY · PI HUETTEMANN, MAIK · 2017 to 2020
$1.5M
NCI NIH HHS P50 CA186786NIGMS NIH HHS R01 GM116807NIH HHS R01 GM116807
6 · The paper itself

Abstract

Prostate cancer is the second leading cause of cancer-related death in men. Two classic cancer hallmarks are a metabolic switch from oxidative phosphorylation (OxPhos) to glycolysis, known as the Warburg effect, and resistance to cell death. Cytochrome

Indexed as

ApoptosisWarburg Effect, OncologicAcetylationAnimalsCardiolipinsCaspase 3Cell Line, TumorCrystallography, X-RayCytochromes cElectron Transport Complex IVHumansLysineMaleMiceMolecular Dynamics SimulationMutationCardiolipinsCaspase 3Cytochromes cElectron Transport Complex IVLysinePeroxidaseReactive Oxygen Speciesacetylationapoptosiscell signalingcytochrome ccytochrome c oxidaseprostate cancerreactive oxygen speciesWarburg effect

Identifiers

PMID33916826
PMCPMC8066186
OpenAlexW3146759115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.