Evidence map›Paper›PMID 33916743›Full record

ArticleMolecules (Basel, Switzerland)2021

Online In-Tube Solid-Phase Microextraction Coupled to Liquid Chromatography-Tandem Mass Spectrometry for the Determination of Tobacco-Specific Nitrosamines in Hair Samples.

Atsushi Ishizaki, Hiroyuki Kataoka

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. A review of the modern principles and applications of solid-phase extraction techniques in chromatographic analysis.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Atsushi IshizakiSchool of Pharmacy, Shujitsu University, Nishigawara, Okayama 703-8516, Japan.
Hiroyuki KataokaSchool of Pharmacy, Shujitsu University, Nishigawara, Okayama 703-8516, Japan.
Shujitsu University · JP

Funding

Smoking Research Foundation None
6 · The paper itself

Abstract

Active and passive smoking are serious public health concerns Assessment of tobacco smoke exposure using effective biomarkers is needed. In this study, we developed a simultaneous determination method of five tobacco-specific nitrosamines (TSNAs) in hair by online in-tube solid-phase microextraction (SPME) coupled to liquid chromatography-tandem mass spectrometry (LC-MS/MS). TSNAs were extracted and concentrated on Supel-Q PLOT capillary by in-tube SPME and separated and detected within 5 min by LC-MS/MS using Capcell Pak C18 MGIII column and positive ion mode multiple reaction monitoring systems. These operations were fully automated by an online program. The calibration curves of TSNAs showed good linearity in the range of 0.5-1000 pg mL

Indexed as

Solid Phase MicroextractionTandem Mass SpectrometryAdultAgedChromatography, LiquidFemaleHairHumansMaleMiddle AgedNicotianaNitrosaminesReproducibility of ResultsYoung AdultNitrosaminesexposure biomarkershairin-tube solid-phase microextraction (SPME)liquid chromatography-tandem mass spectrometry (LC–MS/MS)tobacco-specific nitrosamines

Identifiers

PMID33916743
PMCPMC8038370
OpenAlexW3148022781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.