Evidence map›Paper›PMID 33916674›Full record

ArticleJournal of clinical medicine2021

Multidisciplinary Unit Improves Pregnancy Outcomes in Women with Rheumatic Diseases and Hereditary Thrombophilias: An Observational Study.

Isabel Añón-Oñate, Rafael Cáliz-Cáliz, Carmen Rosa-Garrido, María José Pérez-Galán, Susana Quirosa-Flores, Pedro L Pancorbo-Hidalgo

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Isabel Añón-OñateDepartment of Rheumatology, Jaén University Hospital, 23007 Jaén, Spain.ORCID 0000-0002-3633-3224
Rafael Cáliz-CálizDepartment of Rheumatology, Virgen de las Nieves University Hospital, 18012 Granada, Spain.
Carmen Rosa-GarridoDepartment of Statistics, Foundation FIBAO, Jaén University Hospital, 23007 Jaén, Spain.ORCID 0000-0003-4677-2199
María José Pérez-GalánDepartment of Rheumatology, Jaén University Hospital, 23007 Jaén, Spain.
Susana Quirosa-FloresDepartment of Rheumatology, Virgen de las Nieves University Hospital, 18012 Granada, Spain.
Pedro L Pancorbo-HidalgoDepartment of Nursing, Faculty of Health Sciences, University of Jaén, 23003 Jaén, Spain.ORCID 0000-0002-0092-6095
Hospital Universitario Virgen de las Nieves · ESUniversidad de Jaén · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatic diseases (RD) and hereditary thrombophilias (HT) can be associated with high-risk pregnancies. This study describes obstetric outcomes after receiving medical care at a multidisciplinary consultation (MC) and compares adverse neonatal outcomes (ANOs) before and after medical care at an MC. This study is a retrospective observational study among pregnant women with RD and HT treated at an MC of a university hospital (southern Spain) from 2012 to 2018. Absolute risk reduction (ARR) and number needed to treat (NNT) were calculated. A total of 198 pregnancies were registered in 143 women (112 with RD, 31 with HT), with 191 (96.5%) pregnancies without ANOs and seven (3.5%) pregnancies with some ANOs (five miscarriages and two foetal deaths). Results previous to the MC showed 60.8% of women had more than one miscarriage, with 4.2% experiencing foetal death. MC reduced the ANO rate by AAR = 60.1% (95%CI: 51.6-68.7%). The NNT to avoid one miscarriage was 1.74 (95%CI: 1.5-2.1) and to avoid one foetal death NNT = 35.75 (95CI%: 15.2-90.9). A total of 84.8% of newborns and 93.2% of women did not experience any complication. As a conclusion, the follow-up of RD or HT pregnant women in the MC drastically reduced the risk of ANOs in this population with a previous high risk.

Indexed as

antiphospholipid syndromefoetal deathhereditary thrombophiliasmiscarriagemultidisciplinary consultationpregnancyrheumatic diseasessystemic lupus erythematosus

Identifiers

PMID33916674
PMCPMC8038315
OpenAlexW3148475275

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.