ArticleEntropy (Basel, Switzerland)2021
Brain Dynamics Altered by Photic Stimulation in Patients with Alzheimer's Disease and Mild Cognitive Impairment.
Article in Entropy (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Dynamic Mode Decomposition-Based Clustered Pattern Projection for Reliable Alzheimer's Disease Detection from EEG.Diagnostics (Basel, Switzerland) · 2026Article
- Interpretable AI for neural signal decoding in dementia: an EEG ensemble approach to differential diagnosis.Frontiers in neuroinformatics · 2026Article
- Exploring the Relationship between Behavioral and Neurological Impairments Due to Mild Cognitive Impairment: Correlation Study between Virtual Kiosk Test and EEG-SSVEP.Sensors (Basel, Switzerland) · 2024Article
- Effectiveness of binaural beat music combined with rhythmical photic stimulation on older people with depressive symptoms in long-term care institution: a quasi-experimental pilot study.Aging clinical and experimental research · 2024Article
- Toward the Identification of Neurophysiological Biomarkers for Alzheimer's Disease in Down Syndrome: A Potential Role for Cross-Frequency Phase-Amplitude Coupling Analysis.Aging and disease · 2023Review
- Network-level permutation entropy of resting-state MEG recordings: A novel biomarker for early-stage Alzheimer's disease?Network neuroscience (Cambridge, Mass.) · 2022Article
- Reduced System Complexity of Heart Rate Dynamics in Patients with Hyperthyroidism: A Multiscale Entropy Analysis.Entropy (Basel, Switzerland) · 2022Article
- Dysfunction of Emotion Regulation in Mild Cognitive Impairment Individuals Combined With Depressive Disorder: A Neural Mechanism Study.Frontiers in aging neuroscience · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Individuals with mild cognitive impairment (MCI) are at high risk of developing Alzheimer's disease (AD). Repetitive photic stimulation (PS) is commonly used in routine electroencephalogram (EEG) examinations for rapid assessment of perceptual functioning. This study aimed to evaluate neural oscillatory responses and nonlinear brain dynamics under the effects of PS in patients with mild AD, moderate AD, severe AD, and MCI, as well as healthy elderly controls (HC). EEG power ratios during PS were estimated as an index of oscillatory responses. Multiscale sample entropy (MSE) was estimated as an index of brain dynamics before, during, and after PS. During PS, EEG harmonic responses were lower and MSE values were higher in the AD subgroups than in HC and MCI groups. PS-induced changes in EEG complexity were less pronounced in the AD subgroups than in HC and MCI groups. Brain dynamics revealed a "transitional change" between MCI and Mild AD. Our findings suggest a deficiency in brain adaptability in AD patients, which hinders their ability to adapt to repetitive perceptual stimulation. This study highlights the importance of combining spectral and nonlinear dynamical analysis when seeking to unravel perceptual functioning and brain adaptability in the various stages of neurodegenerative diseases.
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