Evidence map›Paper›PMID 33916580›Full record

ReviewBiosensors2021

Recent Advances in the Fabrication and Functionalization of Flexible Optical Biosensors: Toward Smart Life-Sciences Applications.

Bruno Miranda, Ilaria Rea, Principia Dardano, Luca De Stefano, Carlo Forestiere

Abstract readReview
In one paragraph

Review in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bruno MirandaInstitute of Applied Sciences and Intelligent Systems, Unit of Naples, National Research Council, Via P. Castellino 111, 80131 Napoli, Italy.ORCID 0000-0002-8746-833X
Ilaria ReaInstitute of Applied Sciences and Intelligent Systems, Unit of Naples, National Research Council, Via P. Castellino 111, 80131 Napoli, Italy.ORCID 0000-0003-0568-9911
Principia DardanoInstitute of Applied Sciences and Intelligent Systems, Unit of Naples, National Research Council, Via P. Castellino 111, 80131 Napoli, Italy.ORCID 0000-0002-0616-3914
Luca De StefanoInstitute of Applied Sciences and Intelligent Systems, Unit of Naples, National Research Council, Via P. Castellino 111, 80131 Napoli, Italy.ORCID 0000-0002-9442-4175
Carlo ForestiereDepartment of Electrical Engineering and Information Technology, University of Naples Federico II, Via Claudio 21, 80125 Napoli, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last 30 years, optical biosensors based on nanostructured materials have obtained increasing interest since they allow the screening of a wide variety of biomolecules with high specificity, low limits of detection, and great sensitivity. Among them, flexible optical platforms have the advantage of adapting to non-planar surfaces, suitable for in vivo and real-time monitoring of diseases and assessment of food safety. In this review, we summarize the newest and most advanced platforms coupling optically active materials (noble metal nanoparticles) and flexible substrates giving rise to hybrid nanomaterials and/or nanocomposites, whose performances are comparable to the ones obtained with hard substrates (e.g., glass and semiconductors). We focus on localized surface plasmon resonance (LSPR)-based and surface-enhanced Raman spectroscopy (SERS)-based biosensors. We show that large-scale, cost-effective plasmonic platforms can be realized with the currently available techniques and we emphasize the open issues associated with this topic.

Indexed as

Biosensing TechniquesBiological Science DisciplinesMetal NanoparticlesNanocompositesSpectrum Analysis, RamanSurface Plasmon Resonancedisease early-diagnosisflexible hybrid materialsLSPR-based biosensorsnanocomposite materialsnanofabrication techniquesoptical biosensorsSERS-based biosensors

Identifiers

PMID33916580
PMCPMC8066870

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.