Evidence map›Paper›PMID 33916522›Full record

ArticleInternational journal of molecular sciences2021

Molecular Analysis of

Qing Ye, Rehab Mohamed, Duaa Dakhlallah, Marieta Gencheva, Gangqing Hu, Martin C Pearce, Siva Kumar Kolluri, Clay B Marsh, Timothy D Eubank, Alexey V Ivanov and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Translational lung cancer research · 2026
    Article
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  6. Heliyon · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Qing YeWVU Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.
Rehab MohamedWVU Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.
Duaa DakhlallahWVU Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0002-6288-4927
Marieta GenchevaDepartment of Microbiology, Immunology & Cell Biology, West Virginia University, Morgantown, WV 26506, USA.
Gangqing HuWVU Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0001-5453-6888
Martin C PearceCancer Research Laboratory, Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331, USA.
Siva Kumar KolluriCancer Research Laboratory, Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331, USA.
Clay B MarshDepartment of Medicine, West Virginia University, Morgantown, WV 26506, USA.
Timothy D EubankWVU Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0002-8225-7824
Alexey V IvanovWVU Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0002-8617-4604
Nancy Lan GuoWVU Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0002-8050-6268
West Virginia University · USOregon State University · US

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI Travis Salisbury · 2012 to 2026
$61.1M
Southeast Xlerator NetworkUT2GM130174 · NIGMS · XLERATEHEALTH, LLC · PI KRENTSEL, EUGENE, MCCLURE, IAN D · 2018 to 2020
$3.7M
NIGMS NIH HHS P20 GM103434NIGMS NIH HHS U54 GM104942NIH HHS UT2GM130174
6 · The paper itself

Abstract

Our previous study found that zinc finger protein 71 (ZNF71) mRNA expression was associated with chemosensitivity and its protein expression was prognostic of non-small-cell lung cancer (NSCLC). The Krüppel associated box (KRAB) transcriptional repression domain is commonly present in human zinc finger proteins, which are linked to imprinting, silencing of repetitive elements, proliferation, apoptosis, and cancer. This study revealed that

Indexed as

Drug Resistance, NeoplasmGene Expression Regulation, NeoplasticCarcinoma, Non-Small-Cell LungCell Line, TumorDisease-Free SurvivalDocetaxelFemaleHumansKruppel-Like Transcription FactorsLung NeoplasmsMaleNeoplasm ProteinsPaclitaxelProtein IsoformsSurvival RateDocetaxelKruppel-Like Transcription FactorsNeoplasm ProteinsPaclitaxelProtein IsoformsZNF71 protein, humanchemoresponseCRISPR-Cas9EMTKRAB isoformprognosisproliferationRNAizinc finger protein

Identifiers

PMID33916522
PMCPMC8038441
OpenAlexW3142374082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.