Evidence map›Paper›PMID 33916503›Full record

ArticleCells2021

Acute Ischemic Stroke at High Altitudes in China: Early Onset and Severe Manifestations.

Moqi Liu, Mingzong Yan, Yong Guo, Zhankui Xie, Rui Li, Jialu Li, Changhong Ren, Xunming Ji, Xiuhai Guo

Abstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Stroke in High-Altitude Areas.Brain and behavior · 2025
    Review
  11. Article
  12. Emerging Stroke Risk Factors: A Focus on Infectious and Environmental Determinants.Journal of cardiovascular development and disease · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Recommendations for traveling to altitude with neurological disorders.Journal of central nervous system disease · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Moqi LiuDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Mingzong YanDepartment of Neurology, Yantai Penglai Traditional Chinese Medicine Hospital, Yantai 622110, China.
Yong GuoDepartment of Neurology, Yushu People's Hospital, Yushu 815000, China.
Zhankui XieDepartment of Neurology, Huzhu People's Hospital, Haidong 810500, China.
Rui LiDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Jialu LiDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Changhong RenLaboratory of Hypoxia, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Xunming JiDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Xiuhai GuoDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

Funding

"Sail Plan" Key Medical Specialty ZYLX202139the National Key R&D Program of China 2017YFC1307903
6 · The paper itself

Abstract

The detailed characteristics of strokes at high altitudes in diverse nations have not been extensively studied. We retrospectively enrolled 892 cases of first-ever acute ischemic strokes at altitudes of 20, 2550, and 4200 m in China (697 cases from Penglai, 122 cases from Huzhu, and 73 cases from Yushu). Clinical data and brain images were analyzed. Ischemic strokes at high altitudes were characterized by younger ages (69.14 ± 11.10 vs. 64.44 ± 11.50 vs. 64.45 ± 14.03,

Indexed as

AltitudeAgedAge of OnsetBrain InfarctionChinaFemaleGeographyHumansIschemic StrokeMaleMiddle AgedRisk FactorsSoftwareStrokeVital Signsacute ischemic strokealtitudeneuroimagingpolycythemiarisk factors

Identifiers

PMID33916503
PMCPMC8067425

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.