ArticleCells2021
Effects of Genotypes and Treatment on Oxygenscan Parameters in Sickle Cell Disease.
Open access · goldAbstract read
In one paragraph
Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Baseline characteristics of Ghanaian children and adults enrolled in PIVOT, a randomised clinical trial of hydroxyurea in HbSC disease in sub-Saharan Africa.British journal of haematology · 2024Trial
- A mouse model for hemoglobin SC disease recapitulates characteristic human pathologies.Blood advances · 2025Article
- The role of red blood cell characteristics and viscosity in sickle cell retinopathy and maculopathy.British journal of haematology · 2025Article
- A novel composition of endogenous metabolic modulators improves red blood cell properties in sickle cell disease.EJHaem · 2024Article
- Oxygen gradient ektacytometry-derived biomarkers are associated with acute complications in sickle cell disease.Blood advances · 2024Article
- Increased retention of functional mitochondria in mature sickle red blood cells is associated with increased sickling tendency, hemolysis and oxidative stress.Haematologica · 2023Article
- Simultaneous quantification of blood rheology and oxygen saturation to evaluate affinity-modifying therapies in sickle cell disease.Lab on a chip · 2022Article
- Oxygen gradient ektacytometry does not predict pain in children with sickle cell anaemia.British journal of haematology · 2022Article
- Article
- Nocturnal Hypoxemia Rather Than Obstructive Sleep Apnea Is Associated With Decreased Red Blood Cell Deformability and Enhanced Hemolysis in Patients With Sickle Cell Disease.Frontiers in physiology · 2021Article
- Priming With Red Blood Cells Allows Red Blood Cell Exchange for Sickle Cell Disease in Low-Weight Children.Frontiers in medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 6 institutions in 3 countries.
Camille BoissonLaboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Team « Vascular Biology and Red Blood Cell », Université Claude Bernard Lyon 1, Université de Lyon, 69008 Lyon, France.ORCID 0000-0002-4208-8376
Minke A E RabCentral Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht University, 85500, 3508 GA Utrecht, The Netherlands.
Elie NaderLaboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Team « Vascular Biology and Red Blood Cell », Université Claude Bernard Lyon 1, Université de Lyon, 69008 Lyon, France.ORCID 0000-0002-6054-2456
Céline RenouxLaboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Team « Vascular Biology and Red Blood Cell », Université Claude Bernard Lyon 1, Université de Lyon, 69008 Lyon, France.
Celeste KanneDepartment of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, TX 77030, USA.
Jennifer BosCentral Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht University, 85500, 3508 GA Utrecht, The Netherlands.
Brigitte A van OirschotCentral Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht University, 85500, 3508 GA Utrecht, The Netherlands.
Philippe JolyLaboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Team « Vascular Biology and Red Blood Cell », Université Claude Bernard Lyon 1, Université de Lyon, 69008 Lyon, France.ORCID 0000-0002-2351-9441
Romain FortLaboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Team « Vascular Biology and Red Blood Cell », Université Claude Bernard Lyon 1, Université de Lyon, 69008 Lyon, France.ORCID 0000-0003-0773-3883
Alexandra GauthierLaboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Team « Vascular Biology and Red Blood Cell », Université Claude Bernard Lyon 1, Université de Lyon, 69008 Lyon, France.
Emeric StaufferLaboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Team « Vascular Biology and Red Blood Cell », Université Claude Bernard Lyon 1, Université de Lyon, 69008 Lyon, France.
Solene PoutrelLaboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Team « Vascular Biology and Red Blood Cell », Université Claude Bernard Lyon 1, Université de Lyon, 69008 Lyon, France.
Kamila KebailiLaboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Team « Vascular Biology and Red Blood Cell », Université Claude Bernard Lyon 1, Université de Lyon, 69008 Lyon, France.
Giovanna CannasDépartement de Médecine Interne, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69008 Lyon, France.
Nathalie GarnierInstitut d'Hématologie et d'Oncologie Pédiatrique, Hospices Civils de Lyon, 69008 Lyon, France.
Cécile RenardInstitut d'Hématologie et d'Oncologie Pédiatrique, Hospices Civils de Lyon, 69008 Lyon, France.
Olivier HequetApheresis Unit, Etablissement Français du Sang Rhône Alpes, Centre Hospitalier Lyon Sud Pierre Bénite, 69310 Pierre Bénite, France.
Arnaud HotDépartement de Médecine Interne, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69008 Lyon, France.
Yves BertrandInstitut d'Hématologie et d'Oncologie Pédiatrique, Hospices Civils de Lyon, 69008 Lyon, France.
Richard van WijkCentral Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht University, 85500, 3508 GA Utrecht, The Netherlands.
Vivien A SheehanDepartment of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, TX 77030, USA.
Eduard J van BeersVan Creveldkliniek, University Medical Center Utrecht, Utrecht University, 85500, 3508 GA Utrecht, The Netherlands.
Philippe ConnesLaboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Team « Vascular Biology and Red Blood Cell », Université Claude Bernard Lyon 1, Université de Lyon, 69008 Lyon, France.ORCID 0000-0002-9232-0268
Université Claude Bernard Lyon 1 · FRUtrecht University · NLInstitut d’Hématologie et d’Oncologie Pédiatrique · FRBaylor College of Medicine · USHospices Civils de Lyon · FRHôpital Lyon Sud · FR
Funding
Eurostars estar18105
Abstract
(1) Background: The aim of the present study was to compare oxygen gradient ektacytometry parameters between sickle cell patients of different genotypes (SS, SC, and S/β
Indexed as
AdultAnemia, Sickle CellCell AggregationChild, PreschoolErythrocytesFemaleGenotypeHospitalizationHumansMaleOxygenYoung AdultOxygenacute complicationclinical severityoxygenscanred blood cell deformabilitysickle cell disease
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.