Evidence map›Paper›PMID 33916489›Full record

ReviewVaccines2021

The COVID-19 Vaccines: Recent Development, Challenges and Prospects.

Yuxin Yan, Yoongxin Pang, Zhuoyi Lyu, Ruiqi Wang, Xinyun Wu, Chong You, Haitao Zhao, Sivakumar Manickam, Edward Lester, Tao Wu and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Article
  3. COVID-19 vaccines: current and future challenges.Frontiers in pharmacology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Yuxin YanDepartment of Chemical and Environmental Engineering, University of Nottingham Ningbo China, Ningbo 315100, China.
Yoongxin PangNew Materials Institute, University of Nottingham Ningbo China, Ningbo 315042, China.
Zhuoyi LyuDepartment of Chemical and Environmental Engineering, University of Nottingham Ningbo China, Ningbo 315100, China.
Ruiqi WangNew Materials Institute, University of Nottingham Ningbo China, Ningbo 315042, China.
Xinyun WuNew Materials Institute, University of Nottingham Ningbo China, Ningbo 315042, China.ORCID 0000-0003-4131-0577
Chong YouBeijing International Center for Mathematical Research, Peking University, Beijing 100871, China.
Haitao ZhaoMITMECHE, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Sivakumar ManickamPetroleum and Chemical Engineering, Faculty of Engineering, Universiti Teknologi Brunei, Bandar Seri Begawan BE1410, Brunei.ORCID 0000-0001-9102-4013
Edward LesterDepartment of Chemical and Environmental Engineering, University of Nottingham, Nottingham NG7 2RD, UK.ORCID 0000-0003-1060-103X
Tao WuDepartment of Chemical and Environmental Engineering, University of Nottingham Ningbo China, Ningbo 315100, China.ORCID 0000-0001-6469-9613
Cheng Heng PangNew Materials Institute, University of Nottingham Ningbo China, Ningbo 315042, China.ORCID 0000-0003-1616-6614
University of Nottingham Ningbo China · CNMassachusetts Institute of Technology · USPeking University · CNUniversiti Teknologi Brunei · BNUniversity of Nottingham · GB

Funding

Ningbo Municipal Bureau of Science and Technology 2018A610069Ningbo Municipal Bureau of Science and Technology 2018B10022Science and Technology Department of Zhejiang Province 2020E10018
6 · The paper itself

Abstract

The highly infectious coronavirus disease 2019 (COVID-19) associated with the pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to become a global pandemic. At present, the world is relying mainly on containment and hygiene-related measures, as well as repurposed drugs to control the outbreak. The development of COVID-19 vaccines is crucial for the world to return to pre-pandemic normalcy, and a collective global effort has been invested into protection against SARS-CoV-2. As of March 2021, thirteen vaccines have been approved for application whilst over 90 vaccine candidates are under clinical trials. This review focuses on the development of COVID-19 vaccines and highlights the efficacy and vaccination reactions of the authorised vaccines. The mechanisms, storage, and dosage specification of vaccine candidates at the advanced stage of development are also critically reviewed together with considerations for potential challenges. Whilst the development of a vaccine is, in general, in its infancy, current progress is promising. However, the world population will have to continue to adapt to the "new normal" and practice social distancing and hygienic measures, at least until effective vaccines are available to the general public.

Indexed as

coronavirusCOVID-19global pandemicSARS-CoV-2vaccines

Identifiers

PMID33916489
PMCPMC8067284
OpenAlexW3148140691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.